Abstract:Objective To investigate the influence of hypothyroidism on pregnancy outcomes and fetuses in pregnant women.Methods From March 2017 to April 2018,52 patients with hypothyroidism during pregnancy and 52 healthy pregnant women were selected as subjects.The patients with hypothyroidism during pregnancy were classified into the observation group,and the healthy pregnant women were selected as the control group.The thyroid function,pregnancy outcomes and fetal conditions were observed in the two groups.Results With regard to thyroid function,the thyroid stimulating hormone (TSH)of the observation group was higher than that of the control group,and the level of free thyroxine (FT4)was lower compared with that in the control group with statistical differences (P<0.05).There were no significant differences in pregnancy outcomes such as the incidence of postpartum hemorrhage,placenta previa and placental abruption between the two groups (P>0.05).The incidence of preterm birth and anemia in the observation group was higher than that in the control group with statistical significance (P<0.05).There was no significant difference in fetal malformation between the two groups (P>0.05).The incidence of low birth weight and fetal distress in the observation group was higher than that in the control group (P<0.05).Conclusion Hypothyroidism in pregnant women can have adverse effects on pregnancy outcomes and fetal development,which can increase the incidence of fetal preterm birth and seriously harm the health of the fetus.Early screening,detection and treatment can avoid adverse effects on the fetus,and is of great importance in clinical practice.