Characteristics and treatment outcome analysis of children with Henoch-Schönlein purpura complicated with Mycoplasm pneumoniae infection
CAI Mian-shan1FANG Bing-xiong2▲ HUANG Xu-dong1CHEN Jun3XIE Cheng1
1.Department of Pediatrics，Puning People′s Hospital，Guangdong Province，Puning 515300，China;
2.Department of Clinical Laboratory，Puning People′s Hospital，Guangdong Province，Puning 515300，China;
3.Department of Prevention and Health Section，Peking University Shenzhen Hospital，Guangdong Province，Shenzhen 51800，China
Abstract：Objective To explore and analyze the clinical characteristics and treatment outcome of children with Henoch-Schönlein purpura （HSP）complicated with Mycoplasma pneumoniae infection，and to analyze the correlation between the recurrence of HSP and Mycoplasma pneumoniae infection.Methods Altogether 180 cases of patients with HSP and who received treatment in Puning People′s Hospital from March 2016 to November 2017 were selected as research objects according to the double blind method，and were divided into 95 cases of Mycoplasma infection group and 85 cases of non Mycoplasma infection group according to DNA test results of patients with Mycoplasma pneumoniae.Then，the clinical characteristics were analyzed and patients were given the treatment，and the each indexes changes of biochemical test and blood routine test after the treatment of two groups of patients were compared，and the hospitalization time and recurrence of the two groups were observed.Results The levels of total cholesterol （TC），aspartate aminotransferase （AST）and alanine aminotransferase （ALT）in Mycoplasma infection group were higher than those in non Mycoplasma infection group （P＜0.05）.The levels of white blood cell count （WBC），red blood cell count（RBC），platelet count（PLT）and hemoglobin （Hb）in Mycoplasma infection group were higher than those in the non Mycoplasma infection group （P＜0.05）.The hospitalization time in the Mycoplasma infection group was longer than that in the non Mycoplasma infection group，and the recurrence rate was higher than that in the non-Mycoplasma infection group，the differences were statistically significant（P＜0.05）.Conclusion The recurrence of patients with HSP is influenced by the infection factors of Mycoplasma pneumonia，which it is necessary to detect Mycoplasma pneumoniae DNA in patients with HSP as early as possible，and timely diagnose and treat，so as to reduce the recurrence rate of patients with HSP.
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