Abstract：Objective To investigate the influence of preoperative yellow reduction of bile duct on the curative effect and prognosis of hilar cholangiocarcinoma.Methods From March 2015 to March 2017,78 patients with hilar cholangiocarcinoma were selected and randomly divided into the experimental group and the reference group according to the order of treatment,with 39 patients in each group.The patients in the control group were treated with direct hepatectomy,the patients in the experimental group were treated with percutaneous transhepatic bile duct drainage before hepatectomy.The changes of liver function before and after treatment were observed in the experimental group,and the related indexes,postoperative complications and 1 year mortality were analyzed and compared between the two groups.Results The liver function indexes such as TB,ALT,γ-GT and ALP in the experimental group after treatment were all lower than those before treatment,the difference was statistically significant(P＜0.05).There was no significant difference in operative time,hospitalization time and blood transfusion volume between the two groups (P＞0.05),the amount of intraoperative blood loss in the experimental group was less than that in the control group,the difference was statistically significant(P＜0.05).There was no significant difference in postoperative complications and 1-year mortality between the two groups (P＞0.05).Conclusion Preoperative yellow reduction of bile duct can effectively improve liver function of patients with hilar cholangiocarcinoma,but it can not significantly reduce postoperative complications and mortality.Patients with poor preoperative liver function can be treated with selective yellow reduction.
刘云峰. 术前胆道减黄对肝门部胆管癌手术患者疗效及预后的影响[J]. 中国当代医药, 2019, 26(2): 77-79.
LIU Yun-feng. Influence of preoperative yellow reduction of bile duct on curative effect and prognosis of patients with hilar cholangiocarcinoma. 中国当代医药, 2019, 26(2): 77-79.
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