Clinical effect of Kangfuxin Solution combined with Somatostatin in the treatment of upper gastrointestinal hemorrhage of liver cirrhosis and its influence on hemodynamics
ZHA Hong-qun MAO Pin-ting WEI LingWU QiZOU Hong
Department of Pharmacy，the First People′s Hospital of Jiujiang City in Jiangxi Province，Jiujiang 332000，China
Abstract：Objective To explore the clinical efficacy of Kangfuxin Solution combined with somatostatin on cirrhotic portal hypertensive upper gastrointestinal bleeding and its influence on hemodynamics.Methods A total of 84 patients with cirrhotic portal hypertensive upper gastrointestinal hemorrhage admitted to the First People′s Hospital of Jiujiang City from January 2017 to June 2018 were selected and randomly divided into the case group and the control group，42 cases in each group.The control group was given conventional supportive therapy and Somatostatin，the case group was supplemented with Kangfuxin Solution on the basis of the control group.The clinical efficacy，hemostasis time，blood transfusion volume，rebleeding rate，hospitalization time，venous blood flow and adverse reactions were observed in the two groups.Results The total effective rate of the case group was 95.24%，which was higher than that of the control group （80.95%），and the difference was statistically significant （P＜0.05）.The hemostasis time and the hospitalization time in the case group were shorter than those in the control group，the transfusion volume was less than that of the control group，and the rebleeding rate in the case group was lower than that in the control group，and the differences were statistically significant （P＜0.05）.After treatment，the portal venous blood flow and splenic venous blood flow in the case group were less than those in the control group，and the differences were statistically significant（P＜0.05）.The total incidence of adverse reactions in the case group was 4.76%，which was lower than 23.81%in the control group，and the difference was statistically significant （P＜0.05）.Conclusion Kangfuxin Solution combined with Somatostatin in the treatment of cirrhotic portal hypertensive upper gastrointestinal bleeding has significant clinical effect，and can achieve faster hemostasis and lower incidence of adverse reactions，thus it is worthy of clinical promotion.
查红群;毛娉婷;魏玲;吴琪;邹红. 康复新液联合生长抑素治疗肝硬化上消化道出血的临床效果及对血流动力学的影响[J]. 中国当代医药, 2019, 26(4): 57-59.
ZHA Hong-qun MAO Pin-ting WEI LingWU QiZOU Hong. Clinical effect of Kangfuxin Solution combined with Somatostatin in the treatment of upper gastrointestinal hemorrhage of liver cirrhosis and its influence on hemodynamics. 中国当代医药, 2019, 26(4): 57-59.
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