Abstract：Objective To observe the effect and safety of inhalation of general anesthesia for fundus examination in preterm infants at different gestational ages.Methods A total of 62 preterm infants with retinopathy with corrected gestational age of 33-64 weeks from October 2016 to October 2017 treated in the ophthalmology clinic of our hospital were selected as objects.They were divided into group A and group B according to the different gestational age,with 31 cases in each group.The corrected gestational age of preterm infants in group A was 33-44 weeks,and the corrected gestational age of preterm infants in group B was over 44-63 weeks.In the two groups of children with retinopathy,the fundus examination was performed with inhalation of 6%of Sevoflurane.The body motion stop time was used as the induction time of anesthesia,and the concentration of Sevoflurane anesthesia was given after 2 times of induction time.The initial concentration of maintenance concentration of the two groups was 3%,and the adjusted range of the inhalation concentration was 0.5%.The duration of anesthesia,the time of anesthesia induction,and the awakening time after the cessation of anesthesia were recorded in the two groups,and the adverse reactions such as vomiting and cough were observed during the induction and maintenance of anesthesia in the two groups.After 1 h of the end of fundus examination,whether there were vomiting and cough during drinking and feeding during in the two groups were observed.Results The average maintenance concentration of group A was(2.4±0.5)%,which was significantly lower than that of group B accounting for(3.1±0.7)%,and the difference was statistically significant(P＜0.05).The average anesthesia maintenance time and the average anesthesia waking time in group A was(493.7±104.5)s and(352.6±157.3)s respectively,the group B was(492.8±114.6)s and(367.1±155.3)s respectively,and there were no statistically significant differences in average anesthesia maintenance time and the average anesthesia waking time between two groups(P＞0.05).The average anesthesia induction time of the group A was(56.4±13.1)s,which was significantly shorter than that in the group B accounting for(75.6±13.2)s,and the difference was statistically significant(P＜0.05).Conclusion In order to ensure the safety of the children,Sevoflurane inhalation anesthesia in preterm infants should be strictly controlled according to the conditions of different gestational ages and the needs of the children.
翁建森;谢海航. 不同胎龄早产儿行眼底检查时吸入全身麻醉的效果及安全性[J]. 中国当代医药, 2018, 25(27): 71-73.
WENG Jian-sen;XIE Hai-hang. Effect and safety of inhalation of general anesthesia for fundus examina‐tion in preterm infants at different gestational ages. 中国当代医药, 2018, 25(27): 71-73.
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