Abstract：Objective To investigate the clinical efficacy of endoscopic photodynamic minimally invasive techniques in the treatment of cholangiocarcinoma.Methods A total of 120 patients with gallbladder cancer who were admitted to our hospital from January 2015 to June 2017 were selected as the study subjects.The patients were randomly divided into study group(60 cases)and control group(60 cases)according to the random number table method.The patients in the control group were given endoscopic stenting.The patients in the study group were given photodynamic therapy on this basis.The quality of life(QOL)scores were compared between the two groups at different times.Results In the scale of quality of life,the physical conditions,social/family conditions,emotional conditions,hepatobiliary tumor-specific symptoms and total QOL scores at 3,6,9 and 12 months postoperatively in the study group were all significantly higher than those before the surgery,and the differences were statistically significant(P＜0.05).In the control group,only the physical conditions,social/family conditions,emotional conditions,hepatobiliary tumor-specific symptoms,and total QOL scores at 3 and 6 months after surgery were significantly higher than those before surgery,and the differences were statistically significant(P＜0.05).The total QOL scores before surgery were compared between the two groups,and the difference was not statistically significant(P＞0.05).The differences of the total QOL scores in the two groups at 6,9 and 12 months after surgery were statistically significant(P＜0.05).The total effective rate in the study group was significantly higher than that in the control group,and the difference was statistically significant(P＜0.05).The overall incidence rate in the study group was significantly lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Endoscopic photodynamic minimally invasive therapy can significantly improve the quality of life of patients.The therapeutic effect is significant,and the incidence rate of adverse reactions is low,which is worthy of widespread clinical promotion and application.
邓平. 内镜光动力微创技术治疗胆管癌的临床效果[J]. 中国当代医药, 2018, 25(23): 112-114转117.
DENG Ping. Clinical effect of endoscopic photodynamic minimally invasive technique in the treatment of cholangiocarcinoma. 中国当代医药, 2018, 25(23): 112-114转117.
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