Abstract：Objective To investigate the effect of Tirofiban Hydrochloride Sodium Chloride Injection combined with cardiovascular intervention treating acute myocardial infarction.Methods Sixty patients with acute myocardial infarction treated in our hospital from June 2015 to December 2017 were selected as study objects and they were randomly divided into the two groups,and there were 30 patients in each group.The control group was treated with cardiovascular intervention.The observation group was treated with Tirofiban Hydrochloride Sodium Chloride Injection on the basis of the control group.The clinical effect and short-term prognosis indexes between the two groups were compared.Results TIMI blood flow grading in the observation group was better than that of the control group,and the difference was statistically significant(P＜0.05).There was no significant difference between the two groups in the activation of platelet before treatment(P＞0.05),after treatment,the CD62P,CD63 and positive expression rate of MPA in the observation group was significantly better than that before treatment and the control group(P＜0.05).The incidence of recurrent acute myocardial infarction,sudden death,malignant arrhythmia,severe bleeding events were significantly lower than those of the control group,and the differences were statistically significant(P＜0.05).Conclusion The clinical effect of Tirofiban Hydrochloride Sodium Chloride Injection combined with cardiovascular intervention treating acute myocardial infarction is more significant,which can reduce the incidence of adverse prognosis,which has high safety and is worth popularizing and applying.
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