Abstract：Objective To explore the influence of levamisole combined with Dangguibuxue decoction on immune function of adult nephrotic syndrome patient. Methods 200 nephrotic syndrome patients from January 2010 to October 2014 in our hospital were selected and randomly divided into the control group and the observation group,100 cases in each group.The control group was given routine western medicine treatment,the observation group was given integrated Chinese and western therapy.The clinical effect,immune function index and the incidence rate of adverse reaction in two groups was compared. Results The total effective rate in the observation group was 94.0％,which was higher than 75.0％inthecontrolgroup,withsignificantdifference（P＜0.05）.Thelevelof IgGand IgAintheobservationgroupafter treatment was higher than that before treatment and in the control group,with significant difference（P＜0.05）.The level of CD3 in the observation group after treatment was lower than that before treatment and in the control group,the level of CD4 and CD4/CD8 in the observation group after treatment was higher than that before treatment and in the control group,with significant difference（P＜0.05）.The incidence rate of adverse reaction and recurrence rate in the observation group was lower than that in the control group,with significant difference（P＜0.05）. Conclusion The effect of levamisole combined with dangguibuxue decoction in the treatment of nephrotic syndrome is significant,which can effective improve immune function,reduce the incidence rate of adverse reaction,it is worthy of clinical promotion and application.
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