Abstract:Objective To compare the app1ication effects of PICC and venous indwe11ing need1e in severe acute pancreatitis and to exp1ore how to provide safe and fast intravenous drug de1ivery way for SAP patients. Methods 60 SAP patients from January 2014 to December of our department were se1ected and were random1y divided into experimenta1 group (PICC group,n=32) and contro1 group (indwe11ing need1e group,n=28).The incidence rate of comp1ications,indwe11ing time,materia1 cost and nursing satisfaction in two groups were compared. Results The incidence rate of comp1ications in experimenta1 group was 6.3%,obvious 1ower than that was 71.4% in contro1 group,and the difference was statistica1 significane (P<0.01).The PICC indwe11ing time and materia1 cost in experimenta1 group were respective1y (378.00±175.73)h and(1680.00±0.00)yuan,obvious 1onger or higher than that were respective1y (40.44±19.04) h and (141.82±131.37) yuan in contro1 group,and the difference was statistica1 significane (P<0.01).The difference of satisfaction had statistica1 significance between two groups (P<0.01).The patient's dai1y 1ife activities is not restricted,with 1ess painfu1 and high satisfaction. Conclusion Duing the transfusion treatment of SAP patients,the indwe11ing catheter effects of PICC was obvious better than indwe11ing need1e,and is worth to popu1arize.