Abstract:ObjectiveTo study the use of PiCCO monitoring techniques to guide fluid resuscitation and EGDT regimes to guide fluid resuscitation in patients with septic shock.Methods90 patients with septic shock treated in our hospital from January 2016 to March 2017 were selected as the subjects,and divided into control group and observation group by random number table method,45 cases in each group.Patients in the control group underwent fluid resuscitation under routine EGDT monitoring,and the patients in the observation group monitored the fluid recovery using the PiCCO technique.The levels of 24 h CVP,MAP,Scv O2,GEDVI,PaO2/FiO2,HR and 24 h after treatment were compared between the two groups.ResultsThe levels of 24 h CVP,MAP,Scv O2,GEDVI,PaO2/FiO2and HR in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).The control rate of the observation group(93.33%)was higher than that of the control group(77.78%),the difference was statistically significant(P<0.05).The mortality of the observation group (2.22%)was significantly lower than that of the control group(6.67%),the difference was statistically significant(P<0.05).ConclusionPiCCO monitoring technique is more accurate and effective than EGDT regimen in fluid resuscitation in patients with septic shock.It can reflect the changes and distribution of liquid in vivo and improve the success rate of rescue.