Abstract：Objective To study the clinical effect of cervical LEEP combined with interferon in the treatment of refractory cervicitis. Methods 83 cases of patients with refractory cervicitis in our hospital from March 2014 to November 2015 were collected and diagnosed.According to the random number tablemethod，83 caseswere divided into operation group and operation and drug group.Patients in the operation group were treated by cervical LEEP surgery，while patients in operation and drug group were given cervical LEEP combined with interferon treatment.Clinical therapeutic effect，occurrence ofwound exudates and cervical hyperplasia etc，time of vaginal average bleeding，time of average row liquid，time ofwound average healing and hospitalization timewere compared in two groups.Results Compared with operation group，clinical therapeutic effectwasmore higher（P＜0.01），occurrence ofwound exudates and cervical hyperplasia etc were lower（P＜0.05）），time of vaginal average bleeding，time of average row liquid，time ofwound average healing and hospitalization time were shorter（P＜0.05）in operation and drug group.Conclusion The clinical effect of LEEP combined with interferon therapy in refractory cervicitis is exact，after operation drugs treatment effectively improving the condition of wound，reducing discharge and bleeding，accelerating wound healing，so as to effectively improve the therapeutic effect，accelerate postoperative recovery and is effective and safe in treatment of refractory cervicitis.
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