Abstract：Objective To explore the clinical effect of double frontal and large bone flap decompression treating refractory diffuse brain swelling after brain injury.Methods 60 cases with refractory diffuse brain swelling after brain injury treated by our hospital from December 2014 to December 2015 were selected as the study subject.60 patients were randomly allocated to control group and observation group according to the random allocation method and there were 30 patients in each group.In control group,conventional reduction of intracranial pressure and dehydration was given but the curative effect was not obvious,Phenobarbital method and other measurses to further reduce the intracranial pressure.Observation group was treated by double frontal and large bone flap decompression on the basis of the treatment of control group.The change of intracranial pressure of patients in two groups was recorded and observed from the patients admitted to the hospital to before operation.Glasgow outcome scale(GOS)score was conducted per month and incidence of corresponding complication was recorded of patients in two groups after operation.Patients were observed for 6 consecutive months.Results There was no significant difference of the level of intracranial pressure between two groups on admission(P>0.05).The level of intracranial pressure of patients in observation group after treatment was significantly reduced compared with before admission,and intracranial pressure in observation group after treatment was significantly than that of control group(P<0.05).The total effective rate of observation group(93.33%)was significantly higher than that of control group(73.33%)(P<0.05).Conclusion Double frontal and large bone flap decompression treating refractory diffuse brain swelling after brain injury has a significant effect,and it can significantly reduce the intracranial pressure of patients,improve clinical efficiency.It is worthy of clinical application.
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