Effect observation of Shenyi Capsules in the maintenance treatment of advanced non-small cell lung cancer
LIU Zun-tao LIHong-yan▲
Department of Cardiothoracic Surgery,Hospital of Integrated Traditional and Western Medicine Affiliated to Nanjing University of Chinese Medicine,Jiangsu Province,Nanjing 210028,China
Abstract：ObjectiveTo invesigate the effect of Shenyi Capsules for advanced non-small cell lung cancer(NSCLC) maintenance treatment.MethodsFrom July 2013 to October 2015,90 cases of advanced NSCLC patients with stage Ⅲb~Ⅳ were divided into control group and study group according to the random number table method,45 cases in each group.Control group was treated with pemetrexed,study group was treated with Shenyi Capsules.Patients of the two groups were treated for four cycles.The rate of total effective,rate of treatment benefit,KPS score,and immune function indexes such as CD3+,CD4+,CD8+,CD4+/CD8+of the two groups before and after treatmentwere compared;the adverse reactions of the two groupswere compared.ResultsThe total effective rate of the study group was 53.33%,and the rate of therapeutic benefitwas 84.44%,which were significantly higher than those of the control group (31.11%,66.67%),the differenceswere statistically significant(P<0.05).After treatment,the total increase rate of KPS score in the study group was significantly higher than that of the control group,and the immune function indexes of the two groups were significantly lower than those before treatment,and study group was higher than those of the control group,the differenceswere statistically significant(P<0.05);there was no serious adverse reactions in two groups.ConclusionShenyi Capsules maintenance treatment can significantly improve the efficiency,the quality of life and immune function of patients with advanced NSCLC,so it isworthy of clinical application.
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