Abstract：ObjectiveTo investigate the effect of drug intervention on quality of life in patients with advanced tumor and depression.MethodsFrom April 2012 to April 2016,214 patients with advanced tumor complicated with standard depression were selected and randomly divided into experimental group(112 cases),control group(102 cases)and control group(102cases).The patients in the experimental group were treated with conventional anti-tumor therapy.on the basis of the treatment of the control group,the patients in the experimental group were treated with one tablet of Flupentixol Melitracen every morning and one tablet of Flupentixol Melitracen every day after lunch,and the patients>60 years old were treated with 1 tablet of Flupentixol Melitracen every day after breakfast.After 1,2,3 and 4 weeks,QOL scale was used to score again.ResultsThe QOL score of the experimental group at week 1-4 was significantly higher than that before treatment(P<0.05).The QOL score of the experimental group was higher than that of the control group(P<0.05),and the side effect of the experimental group was higher than that of the control group(P<0.05).ConclusionDrug intervention of Flupentixol Melitracen can improve QOL of patients with advanced tumor combined with depression,and without obvious adverse reactions,is worthy of clinical application.
高金锁; 王建冰 ;刘玮玮; 杨金珠. 药物干预对晚期肿瘤合并抑郁状态患者生活质量的影响[J]. 中国当代医药, 2018, 25(5): 80-82.
GAO Jin-suo; WANG Jian-bing ;LIU Wei-wei;YANG Jin-zhu. Influence of drug intervention on the quality of life in patients with advanced tumor and depression. 中国当代医药, 2018, 25(5): 80-82.
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