Abstract：Objective To investigate effectiveness of low molecular heparin in the treatment of neonatal sepsis.Methods 58 cases of neonatal septicemia in our hospital from March 2015 to July 2016 were collected and divided into observation group and control group according to admission order,29 cases in each group.Patients in the control group were treated by traditional antibiotic treatment,patients in the observation group were treated with low molecular heparin on the basis of the control group,clinical therapeutic effect,changes of procalcitonin(PCT)and C reactive protein(CRP) levels before and after treatment between two groups were compared.Results Total effective rate in the observation group was 96.55%,higher than 86.21%in the control group,and the difference was statistically significant(P＜0.05).PCT and CRP level after treatment in the observation group was(0.29±0.17)ng/L and(5.52±2.37)mg/L respectively,significantly lower than(5.65±2.18)ng/L and(22.70±5.29 mg/L before treatment(P＜0.05);PCT and CRP level after treatment in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Low molecular heparin combined antibiotics in the treatment of neonatal sepsis has obvious clinical effect,can significantly improve procalcitonin and CRP level,which has high clinical value.
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