Abstract:Objective To observe effect of transverse abdominal fascia block combined with Butorphanol preemptive analgesia in daytime laparoscopic surgery. Methods A total of 90 patients who underwent daytime laparoscopic cholecystectomy in Ganzhou People′s Hospital from January 1, 2021 to April 10, 2021 were selected as the research subjects, and were divided into study group (45 cases) and control group (45 cases) according to random number table. In the study group, 0.01 mg/kg Butorphanol was given intranasally 10 min before induction of anesthesia, while in the control group, the same dose of normal saline was given intranasally. After surgery, bilateral transverse abdominal fascia was blocked under ultrasound guidance in both groups. The dosage of Remifentanil, operation time, anesthesia time, extubation time and stay time in resuscitation room were compared between the two groups. Postoperative analgesia scores were scored at 2, 4, 6, 12 h after surgery and at the time of discharge (T1-T5). The number of additional tramadol patients, the incidence of adverse reactions, analgesic satisfaction and the rate of untimely discharge during postoperative analgesia were analyzed. Results There were no significant differences in Remifentanil dosage, operation time, recovery time, extubation time and stay time in resuscitation room between two groups (P>0.05). The visual analog scale (VAS)score of the study group at T1-T4 were lower than those of the control group, and the differences were statistically significant (P<0.05). The additional number of Tramadol in the study was less than that in the control group, the satisfaction of study group was higher than that of the control group, and the incidence of postoperative nausea, vomiting and lethargy in the study group was lower than the control group, and the differences were statistically significant (P<0.05).There was no significant difference in the rate of untimely discharge between the two groups (P>0.05). Conclusion Ultrason-guided transverse abdominal fascia block combined with nasal preemptive analgesia of butorphano is suitable for analgesia in daytime laparoscopic cholecystectomy, which can provide a good analgesic effect and does not affect the recovery time of patients, with high safety.
Bisgaard T,Kehlet H,Rosenberg J.Pain and convalescence after laparoscopic cholecystectomy[J].Eur J Surg,2001,167(2):84-96.
[5]
Davis GA,Rudy AC,Archer SM,et al.Bioavailability of intranasal butorphanol administered from a single -dose sprayer[J].Am J Health Syst Pharm,2005,62(1):48-53 .
Tang HR,Dong AH,Yan LN.Day surgery versus overnight stay laparoscopic cholecystectomy:A systematic review and meta-analysis[J].Dig Liver Dis,2015,47(7):556-561.
[12]
Baral B,Poudel PR.Comparison of Analgesic Efficacy of Ultrasound Guided Subcostal Transversus Abdominis Plane Block with Port Site Infiltration Following Laparoscopic Cholecystectomy[J].J Nepal Health Res Counc,2019,16(41):457-461.
[13]
Baytar C,Y1lmaz C,Karasu D,et al.Comparison of Ultrasound-Guided Subcostal Transversus Abdominis Plane Block and Quadratus Lumborum Block in Laparoscopic Cholecystectomy:AProspective,Randomized,ControlledClinical Study[J].Pain Res Manag,2019,2019:2815 301.
[14]
Sun Q,Liu SY,Wu HY,et al.Dexmedetomidine as an Adjuvant to Local Anesthetics in Transversus Abdominis Plane Block:A Systematic Review and Meta-analysis[J].Clin J Pain,2019,35(4):375-384.
[15]
Keir A,Rhodes L,Kayal A,et al.Does a transversus abdominis plane (TAP) local anaesthetic block improve pain control in patients undergoing laparoscopic cholecystectomy?[J].Int J Surg,2013,11(9):792-794.
[16]
Karim HMR,Bhakta P,O′Brien P,et al.Bilateral subcostal transversus abdominis plane block as a component of multimodal analgesia[J].Eur J Anaesthesiol,2020,37(1):58-59 .
[17]
Houben AM,Moreau AJ,Detry OM,et al.Bilateral subcostal transversus abdominis plane block does not improve the postoperative analgesia provided by multimodal analgesia after laparoscopic cholecystectomy:A randomised placebo-controlled trial[J].Eur J Anaesthesiol,2019,36(10):772-777.