Clinical study of Carboprost Methyl Suppository for the prevention of postpartum hemorrhage in high-risk parturients immediately after delivery of the fetus
HAN Chun-ping XIAO Wen-ping XIE Qin-ying
Delivery Room,Ganzhou Maternity and Child Health Hospital,Jiangxi Province,Ganzhou 341000,China
摘要目的 探讨卡前列甲酯栓在胎儿娩出后对高危产妇立即塞肛预防产后出血的临床效果。方法 选取2019年1—12月赣州市妇幼保健院收治的206 例胎儿娩出后出血的高危产妇，依照随机数字表法分为对照组与观察组，每组各103 例。对照组给予缩宫素治疗，观察组在对照组的基础上给予卡前列甲酯栓治疗。比较两组的临床相关指标及产中、产后2 h 的出血量，记录两组的胎盘娩出时间、手取胎盘率、胎盘残留率。结果 观察组的胎盘分娩时间≥15 min 者所占比例低于对照组，差异有统计学意义（P<0.05）。观察组的产时、产后2 h 出血量少于对照组，差异有统计学意义（P<0.05）。观察组的手取胎盘率（2.91%）、胎盘残留率（1.94%）低于对照组（10.68%、11.65%），差异有统计学意义（P<0.05）。结论 卡前列甲酯栓在胎儿娩出后对高危产妇立即塞肛预防产后出血的临床效果显著，可显著减少产妇产后出血量，降低手取胎盘率、胎盘残留率。
Abstract：Objective To explore the clinical effect of Carboprost Methyl Suppository for the prevention of postpartum hemorrhage in high-risk parturients immediately after delivery of the fetus.Methods A total of 206 high-risk pregnant women with postpartum hemorrhage in high-risk parturients immediately after delivery of the fetus from January to December 2019 in Ganzhou Maternity and Child Health Hospital were selected,according to the random digital table method,they were divided into the control group and the observation group,103 cases in each group.The control group was treated with Oxytocin,and the observation group was treated with Carboprost Methyl Suppository on the basis of the control group.The clinical related indexes and the amount of postpartum hemorrhage during delivery and 2 hours after delivery were compared between the two groups.The time of delivery of placenta,the rate of manual extraction of placenta and the rate of residual placenta were recorded between the two groups.Results The proportion of placental delivery time ≥15 min in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The amount of bleeding in the observation group during delivery and 2 hours after delivery was less than that in the control group,and the differences were statistically significant(P<0.05).The rate of placenta removal by hand(2.91%)and residual rate of placenta(1.94%)in the observation group were lower than those in the control group(10.68% and 11.65%),and the differences were statistically significant(P<0.05).Conclusion The clinical effect of Carboprost Methyl Suppository in preventing postpartum hemorrhage was significant in the prevention of postpartum hemorrhage in high-risk parturients immediately after delivery,which can significantly reduce the amount of postpartum hemorrhage,and reduce the rate of placenta removal and placenta residue by hand.
韩春萍 ；肖文萍 ；谢勤英. 卡前列甲酯栓在胎儿娩出后针对高危产妇立即塞肛预防产后出血的临床研究[J]. 中国当代医药, 2021, 28(24): 149-151.
HAN Chun-ping ；XIAO Wen-ping； XIE Qin-ying. Clinical study of Carboprost Methyl Suppository for the prevention of postpartum hemorrhage in high-risk parturients immediately after delivery of the fetus. 中国当代医药, 2021, 28(24): 149-151.
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