Abstract:Objective To investigate the clinical efficacy of Zhixue Powder combined with thrombin and Omeprazole in the treatment of acute upper gastrointestinal bleeding.Methods 202 patients with acute upper gastrointestinal bleeding treated in our hospital from February 2012 to February 2016 were selected as research objects.They were randomly divided into experimental group (n=101)and control group (n=101).Thrombin and Omeprazole were provided in both groups.In the experimental group,Zhixue Powder was added.The clinical efficacy,time to stanch bleeding,recurrence rate of bleeding,and adverse reactions were analyzed and compared.Results The total effective rate was 95.04%in the experimental group,much higher than that in the control group accounting for 89.10% (P<0.05).The average hemostasis time was(16.9±2.8)h in the experimental group,significantly shorter than that in the control group[(31.2±3.6)h](P<0.05).The rate of rebleeding was 3%and 18%in the experimental group and control group respectively,and the former one was significantly lower(P<0.05).Conclusion Zhixue Powder combined with thrombin and Omeprazole can significantly shorten the hemostasis time in patients with acute upper gastrointestinal hemorrhage and reduce the rate of rebleeding in a favorable effect,which is worthy of promotion in clinical practice.
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