Abstract:Objective To explore the clinical application value of 890 nm infrared laser in the treatment of diabetic peripheral neuropathy.Methods A total of 80 cases with type 2 diabetes mellitus complicated with diabetic peripheral neuropathy from January 2018 to March 2020 in the Department of Endocrine in the First People′s Hospital of Qinzhou City were randomly divided into two groups,40 case in each group.The control group was received Epalrestat orally before meals,the observation group received 890 nm infrared laser irradiation on the basis of control group.The neurological deficit score (NDS),nerve conduction function of lower limbs and biochemical indexes related to cognitive function (S-100B protein,neuron-specific enolase [NSE]) were compared between the two groups before and after treatment.Results There was no significant difference in NDS scores between the two groups before treatment (P>0.05).The NDS score of the observation group after treatment was lower than that before treatment and lower than that of the control group,with statistical significance (P<0.05).After treatment,the motor and sensory conduction velocity of peroneal nerve in lower limb nerve conduction function of the two groups were higher than those before treatment,and higher than those in the control group,with statistical significance (P<0.05).After one cycle of treatment,the levels of S-100B protein and NSE in the observation group were lower than those before treatment,and lower than those in the control group,and the differences were statistically significant (P<0.05).Conclusion For diabetic peripheral neuropathy patients,890 nm infrared laser irradiation therapy can effectively improve peripheral nerve function,so it also can improve nerve conduction ability.