Abstract：Objective To compare and analyze the clinical efficacy and 1-year follow-up of transurethral plasma enucleation of bladder tumor(TeURBT)and transurethral resection of bladder tumor(TURBT)in the treatment of non-muscular invasive bladder cancer.Methods A retrospective analysis of 92 patients with non-muscular invasive bladder cancer admitted to the Department of Urology in the Dandong Central Hospital from June 2018 to December 2019 was conducted.They were divided into the group A and the group B according to different surgical methods,with 46 patients in each group.The group A were given TURBT operation and the group B were given TeURBT operation.The perioperative indicators,complications,serum indicators and recurrence were compared and analyzed between the two groups.Results The operation time in the group B was longer than that in the group A,while the duration of catheter indwelling,bladder irrigation and hospitalization in the group B were shorter than those in the group A,and the blood loss during operation in the group B was less than that in the group A,with statistically significant differences(P<0.05).The total incidences of postoperative complications in the group B was lower than that in the group A,with statistically significant difference(P<0.05).The expressions of monocyte chemoattractant protein-1(MCP-1),human cartilage glycoprotein-39 (YKL40)and vascular endothelial growth factor(VEGF)at the time of reexamination were lower than those before surgery,with statistically significant differences(P<0.05).But there were no statistically significant differences of MCP-1,YKL40 and VEGF between the two groups (P>0.05).The cumulative recurrence rate at 1 year after operation in the group B was 6.52%,which was lower than that in the group A as 21.74%,with statistically significant difference (P<0.05).Conclusion Both TeURBT and TURBT can achieve significant effects in the treatment of nonmuscular invasive bladder cancer,but TeURBT has more advantages in improving perioperative indicators,and reducing incidence of complications and recurrence rate.
Gun，Danielsson，Per-uno，et al.Bladder health in patients treated with BCG instillations for T1G2-G3 bladder cancer-a follow-up five years after the start of treatment[J].Scand J Urol，2019，52（5-6）：377-384.
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