Abstract:Objective To explore the guiding effect of bispectral index(BIS)monitoring on postoperative sedation treatment in patients with severe preeclampsia.Methods A total of 50 patients with severe preeclampsia treated in Maternal and Child Health Hospital of Jiangxi Province from October 2019 to December 2020 were selected as the research objects.They were divided into control group and observation group according to the random number table method,with 25 cases in each group.Both groups underwent cesarean section surgery.Nitroglycerin and Diazepam injection were used as antihypertensive sedatives.The control group took empirical medications,and the observation group took BIS to monitor the dosage of the drugs,both groups were observed for 48 hours after operation.The mean arterial pressure(MAP)and heart rate (HR)levels before operation,8,24 and 48 hours after operation,and the incidence of eclampsia,postpartum hemorrhage and heart failure at 48 hours after operation of the two groups were compared.Results There were no statistically significant differences in MAP and HR levels between the two groups before surgery(P>0.05).The MAP and HR levels of the two groups at 8,24,and 48 h after surgery were lower than those before surgery,and the MAP and HR levels at 24 h after surgery were lower than those at 8 h after surgery,and the MAP and HR levels at 48 h after surgery were lower than those at 24 h after surgery,the differences were statistically significant(P<0.05).The MAP and HR levels of the observation group at 8,24 and 48 h after surgery were lower than those of the control group,and the differences were statistically significant(P<0.05).The total incidence of postoperative complications in the observation group at 48 h after surgery was lower than that of the control group,the difference was statistically significant(P<0.05).Conclusion BIS monitoring can regulate the dosage of relevant drugs,so as to reduce the levels of MAP and HR in patients with severe preeclampsia,reducing the incidence of postoperative complications,and guiding the drugs to achieve sedative effect.