经皮肾镜手术治疗输尿管结石的效果及对肾功能和并发症的影响

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摘要

目的观察经皮肾镜进行手术治疗患者输尿管结石的效果及对肾功能的影响和并发症情况。方法选取2019年1月～2020年1月辽阳市第五人民医院收治的60例输尿管结石患者作为研究对象。按随机抽签法分为对照组（30例）与干预组（30例）。对照组选择经输尿管镜手术进行取石治疗，干预组经皮肾镜手术进行取石治疗。比较两组患者的结石清除率、手术情况、肾功能以及并发症发生情况。结果干预组的结石清除率高于对照组，手术时间短于对照组，术中出血量多于对照组，住院时间长于对照组，差异有统计学意义（P＜0.05）；两组术后的尿肌酐（Cr）、肾小球滤过率（GFR）、胱抑素C（Cys-C）、尿素氮（BUN）及脂质运载蛋白（NGAL）水平低于术前，差异有统计学意义（P＜0.05）；两组术后的Cr、NGAL水平低于术前，GFR、Cys-C、BUN水平高于术前，差异有统计学意义（P＜0.05）；干预组术后的Cys-C 水平低于对照组，干预组术后的NGAL水平高于对照组，差异有统计学意义（P＜0.05）;干预组并发症总发生率低于对照组，差异有统计学意义（P＜0.05）。结论经皮肾镜进行手术治疗患者输尿管结石的效果显著，能有效地清除结石，改善其肾功能，减少并发症，值得推广应用。

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	孙连贺
	张武杰
	纪洪亮
	郁松涛

关键词 ：经皮肾镜手术, 输尿管结石, 肾功能, 并发症

Abstract：

Objective To observe the effect of percutaneous nephroscope surgery on patients with ureteral calculi and the effect on renal function and complications.Methods A total of 60 patients with ureteral calculi who were admitted to the Fifth People′s Hospital of Liaoyang City from January 2019 to January 2020 were selected as the research subjects.They were randomly divided into control group (30 cases) and intervention group (30 cases).The control group adopted ureteroscopic surgery for stone removal for treatment,the intervention group was treated with percutaneous nephroscope surgery.The stone removal rates,operation status,renal function and complications of the two groups were compared.Results The stone clearance rate of the intervention group was higher than that of the control group,the operation time was shorter than that of the control group,the intraoperative blood loss was more than that of the control group,and the hospital stay was longer than that of the control group,the differences were statistically significant (P＜0.05).The levels of creatinine (Cr),glomerular filtration rate (GFR),cystatin C (Cys-C),blood urea nitrogen (BUN),and lipocalin (NGAL) in the two groups after surgery were lower than those before surgery,the differences were statistically significant (P＜0.05).The levels of Cr and NGAL after surgery in the two groups were lower than those before surgery,while the levels of GFR,Cys-C and BUN were higher than those before surgery,the differences were statistically significant (P＜0.05).The level of Cys-C in intervention group was lower than that in the control group,and the level of NGAL in intervention group was higher than that in the control group,the differences were statistically significant (P＜0.05).The total incidence of complication in that intervention group was lower than that in the control group,the difference was statistically significant (P＜0.05).Conclusion Percutaneous nephroscope surgery is effective in treating patients with ureteral calculi,which can effectively remove calculi,improve renal function,and reduce complications.It is worthy of popularization and application.

Key words： Percutaneous nephroscopy')" href="#">

Percutaneous nephroscopy Ureteral stones Renal function Complication

引用本文:

孙连贺；张武杰；纪洪亮；郁松涛. 经皮肾镜手术治疗输尿管结石的效果及对肾功能和并发症的影响[J]. 中国当代医药, 2021, 28(7): 105-107.
SUN Lian-he；ZHANG Wu-jie ；JI Hong-liang ；YU Song-tao.

Effect of percutaneous nephrolithiasis in the treatment of ureteral calculi and its influence on renal function and complications

. 中国当代医药, 2021, 28(7): 105-107.

链接本文:

http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2021/V28/I7/105

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