Clinical effect comparison of Oxaliplatin combined with Tegafur Gimeracil Oteracil Potassium and Oxaliplatin combined with Raltitrexed in the treatment of patients with advanced colon cancer
MEI Jiang-hua1 XIAO Chun-e2▲
1.Department of Oncology,Songzi People′s Hospital,Hubei Province,Songzi 434200,China;
2.Department of Emergency,Songzi People′s Hospital,Hubei Province,Songzi 434200,China
Abstract:Objective To compare the clinical effects of Oxaliplatin combined with Tegafur Gimeracil Oteracil Potassium and Oxaliplatin combined with Raltitrexed in the treatment of patients with advanced colon cancer.Methods A total of 106 patients with advanced colon cancer admitted to Songzi People′s Hospital from July 2018 to July 2020 were selected as the research subjects.According to the envelope selecting,they were divided into the reference group(53 cases)and the study group(53 cases).The reference group was treated with Oxaliplatin combined with Tegafur Gimeracil Oteracil Potassium,and the study group was treated with Oxaliplatin combined with Raltitrexed.The clinical effects and safety of the two groups were compared.Results The effectiveness rate of treatment in the study group was higher than that of the reference group,with statistical significance(P<0.05).The progression-free survival of the study group was longer than that of the reference group,with statistical significance(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The clinical effect of Oxaliplatin combined with Raltitrexed in the treatment of patients with advanced colon cancer is better than that of Oxaliplatin combined with Tegafur Gimeracil Oteracil Potassium.The survival time of patients is effectively prolonged and has certain safety,which is worthy of clinical promotion and application.
梅江华;肖春娥. 奥沙利铂联合替吉奥与奥沙利铂联合雷替曲塞治疗晚期结肠癌患者的临床效果比较[J]. 中国当代医药, 2021, 28(24): 120-122.
MEI Jiang-hua1 XIAO Chun-e2▲. Clinical effect comparison of Oxaliplatin combined with Tegafur Gimeracil Oteracil Potassium and Oxaliplatin combined with Raltitrexed in the treatment of patients with advanced colon cancer. 中国当代医药, 2021, 28(24): 120-122.