Abstract：Objective To compare the effect of laparoscopic surgery and traditional laparotomy in the treatment of children with complicated appendicitis. Methods From January 2015 to December 2019, 52 cases of children with complicated appendicitis treated in Marina Bay Center Hospital of Dongguan City were selected as the research objects, and they were divided into the minimally invasive group (26 cases) and the laparotomy group (26 cases) by random number table method. The minimally invasive group was treated with laparoscopic surgery, and the laparotomy group was treated with laparotomy surgery. The surgical treatment condition, inflammatory factor levels (C reactive protein [CRP], interleukin-6[IL-6],procalcitonin [PCT]), immune function index such as peripheral blood CD3, CD4 and complications were observed and compared between the two groups. Results The anal exhaust time and hospitalization time in the minimally invasive group were shorter than those in the laparotomy group, and the intraoperative blood loss in the minimally invasive group was less than that in the laparotomy group,the differences were statistically significant (P＜0.05).The levels of CRP, IL-6 and PCT of the two groups after operation were higher than those before operation, and the levels of CRP, IL-6 and PCT after operation in the minimally invasive group were lower than those in the laparotomy group, the differences were statistically significant(P＜0.05).The levels of CD3 and CD4 of the two groups after operation were lower than those before the operation,and the levels of CD3 and CD4 in the minimally invasive group after operation were higher than those in the laparotomy group, the differences were statistically significant (P＜0.05). The total incidence of postoperative complications in the minimally invasive group was lower than that in the laparotomy group,and the difference was statistically significant (P＜0.05). Conclusion For children with complicated appendicitis surgery, compared with traditional laparotomy, laparoscopic surgery has less postoperative inflammatory reaction, less impact on immune function,faster recovery and lower incidence of complications.
叶伟杰；陈家阳；林树文；洪晓城；吉成岗；何应新. 腹腔镜手术和传统开腹手术治疗复杂性阑尾炎患儿的效果比较[J]. 中国当代医药, 2021, 28(16): 36-39.
YE Wei-jie；CHEN Jia-yang；LIN Shu-wen；HONG Xiao-cheng；JI Cheng-gang；HE Ying-xin. Comparison of the effect of laparoscopic surgery and traditional laparotomy in the treatment of children with complicated appendicitis. 中国当代医药, 2021, 28(16): 36-39.
Pogorelic Z，Buljubasic M，Susnjar T，et al.Comparison of Open and Laparoscopic Appendectomy in Children：a 5-year Single Center Experience[J].Indian Pediatr，2019，56（4）：299-303.
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