南昌市某三甲医院围生期孕妇B族链球菌感染现状及妊娠结局分析

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摘要目的分析南昌市某三甲医院围生期孕妇B 族链球菌（GBS）感染现状及对妊娠结局的影响。方法选取2018年4月～2019年3月来该院进行产检并分娩的1137 例围生期孕妇为研究对象，取肛门和生殖道分泌物进行细菌培养，根据培养结果分为感染组和对照组，分析其感染现状及相关影响因素并比较两组不良妊娠结局的发生率。结果 1137 例围生期孕妇共检出GBS 67 例，感染率为5.89%（67/1137）；孕产妇≥35 岁、≥3 次流产史、本科及以上学历的感染率分别为9.63%、11.43%、7.01%，高于＜35 岁、＜3 次流产史、本科以下学历的4.55%、5.33%、3.54%，差异均有统计学意义（P＜0.05）；感染组产褥感染、胎膜早破、早产的发生率分别为16.42%、10.45%、13.43%，均高于对照组的7.20%、5.40%、6.36%，差异有统计学意义（P＜0.05）；感染组新生儿上呼吸道感染、病理性黄疸、新生儿低体重的发生率分别为5.97%、28.36%、7.46%，均高于对照组的1.03%、10.75%、1.96%，差异有统计学意义（P＜0.05）；两组难产、新生儿窒息的发生率比较，差异无统计学意义（P＞0.05）。结论该院围生期孕妇感染GBS 较高，且与孕妇年龄、流产史和学历因素相关。GBS 感染可导致孕妇产褥感染、胎膜早破和早产，并增加了新生儿上呼吸道感染、病理性黄疸、新生儿低体重的发生率，严重影响母婴健康。

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	查固长
	袁丽

关键词 ：围生期孕妇, B 族链球菌, 感染状态, 妊娠结局

Abstract：Objective To analyze the infection status of Group B Streptococci (GBS) in perinatal women in a tertiary hospital in Nanchang City and its effect on pregnancy outcome.Methods From April 2018 to March 2019, a total of 1137 perinatal pregnant women who came to the hospital to perform prenatal examination and have a delivery were selected as the research object.The anus and genital tract secretions were taken for bacterial culture, according to the culture results, they were divided into the infection group and the control group, and the status of infection and its relevant factors were analyzed.In addition, the incidence of adverse pregnancy outcomes was compared between the two groups.Results A total of 67 cases of GBS were detected in the 1137 cases of perinatal pregnant women, the infection rate was 5.89%(67/1137);as for puerperal who ≥35 years old,≥3 times of abortion history,undergraduate and above,the infection rates were 9.63%,11.43%,7.01%respectively,which were higher than the infection rates of puerperal ＜35 years old, ＜3 times of abortion history, bachelor degree or below, which were 4.55%, 5.33%, 3.54%.The differences were statistically significant (P＜0.05).The incidence rates of puerperal infection, premature rupture of membranes, premature delivery in infection group were 16.42%, 10.45% and 13.43% respectively, which were higher than 7.20%, 5.40% and 6.36% of the control group.The differences were statistically significant (P＜0.05).The incidence rates of neonatal upper respiratory tract infection, pathological jaundice , neonatal low weight in infection group were 5.97%, 28.36% and 7.46% respectively, which were higher than 1.03%, 10.75%, 1.96% of the control group.The differences were statistically significant (P＜0.05).There were no significant differences in the incident rates of dystocia and neonatal asphyxia in the two groups.(P＞0.05).Conclusion The incidence of GBS among pregnant women in the perinatal period is higher in the hospital, which is related to the age, abortion history and educational background of pregnant women.GBS infection can lead to maternal puerperal infection, premature rupture of membranes and premature delivery, and increase the incidence of neonatal upper respiratory tract infection, pathological jaundice and low neonatal weight, which seriously affects maternal and infant health.

Key words： Perinatal pregnant women Group B Streptococcus Infection Status;Pregnancy outcome

引用本文:

查固长；袁丽. 南昌市某三甲医院围生期孕妇B族链球菌感染现状及妊娠结局分析[J]. 中国当代医药, 2020, 27(13): 180-182.
ZHA Gu-zhang； YUAN Li. Analysis of infection status of Group B Streptococcus and pregnancy outcomes in perinatal pregnant women in a tertiary hospital in Nanchang City. 中国当代医药, 2020, 27(13): 180-182.

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http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2020/V27/I13/180

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