Abstract: Objective To explore the feasibility of multimode combined therapy in the analgesia after thoracotomy.Methods A total of 60 patients with thoracotomy who were admitted to our hospital from March 2016 to March 2018 were selected as research objects and they were divided into group A (simple self-controlled analgesia), group B (combined with intercostal nerve block on the basis of group A) and group C (combined with intraoperative intercostal nerve protection on the basis of group B) according to different analgesia regimens, with 20 cases in each group.The operation time, chest tube removal time, hospitalization time, and mean arterial pressure (MAP), heart rate (HR), and oxygen saturation (SpO2) before treatment, and 24, 48 h after treatment among the three groups of patients were recorded.Visual analogue scale (VAS) score was used to evaluate the pain after anesthetic awareness, 1 d after chest tube removal and at 1 month and 2 months after operation of the three groups.The incidence of adverse reactions was compared in three groups of patients.Results The chest tube removal time of group C was shorter than that of group A, and the difference was statistically significant (P<0.05).There were no significant differences in the operation time and hospitalization time among the three groups (P>0.05).There were no significant differences in the MAP, HR and SpO2 among the three groups (P>0.05).The MAP and HR of group B and group C were lower than those of group A 24 h after treatment, and the differences were statistically significant (P<0.05).The HR of group B and group C was lower than that of group A 48 h after treatment, and the differences were statistically significant (P<0.05).The HR of group C was lower than that of group B 48 h after treatment, and the difference was statistically significant (P<0.05).The VAS scores of patients in group C after anesthesia, 1 d after removal of chest tube and 1 month after operation were lower than those in group A and group B, and the differences were statistically significant (P<0.05).The VAS scores of group B after anesthesia awareness and 1 d after removal of chest tube were lower than those of group A, and the differences were statistically significant (P<0.05).There were no significant differences in VAS scores among the three groups 2 months after operation (P>0.05).The total incidence rate of adverse reactions in group C was lower than that in group A and group B, and the differences were statistically significant (P<0.05).Conclusion Multimode combined therapy has significant analgesic effect after thoracotomy with fewer adverse reactions.
刘俊;孔羽;曾庆武;李志勇;熊薇. 多模式联合治疗在开胸术后镇痛中的应用效果[J]. 中国当代医药, 2019, 26(12): 98-101.
LIU Jun; KONG Yu ;ZENG Qing-wu; LI Zhi-yong ;XIONG Wei. Application effect of multimode combined therapy in the analgesia after thoracotomy. 中国当代医药, 2019, 26(12): 98-101.