Clinical effect comparison of hemodialysis and peritoneal dialysis in the treatment of renal failure
YU Lan1 ZHOU Yan2
1. Department of Internal Medicine, Chengdu University of Technology Hospital, Sichuan Province, Chengdu 610059,China; 2. Department of Nephrology, the First People′s Hospital of Ziyang, Sichuan Province, Ziyang 641300, China
Abstract：Objective To compare the clinical effect of hemodialysis and peritoneal dialysis in the treatment of renal failure. Methods A total of 200 patients with renal failure admitted to Chengdu University of Technology Hospital and the First People′s Hospital of Ziyang from January 2016 to December 2017 were selected as the study subjects. They were divided into hemodialysis group (treated with hemodialysis method) and peritoneal dialysis group (treated with peritoneal dialysis method) according to the random number table method, with 100 cases in each group. The levels of renal function indicators (blood urea nitrogen [BUN], C-reactive protein [CRP], serum creatinine [Scr]) and changes in hemodynamic parameters (cardiac index [CI], heart rate [HR], mean arterial pressure [MAP]) before and after treatment were compared between the two groups. Results There were no significant differences in the levels of renal function between the two groups before treatment (P＞0.05). The levels of BUN, CRP and Scr in the two groups after treatment were lower than those before treatment, and the differences were statistically significant (P＜0.05). The levels of BUN, CRP and Scr in the hemodialysis group after treatment were lower than those in the peritoneal dialysis group, and the differences were statistically significant (P＜0.05). There were no significant differences in the changes of hemodynamic parameters between the two groups before treatment (P＞0.05). There was no significant difference in CI between the peritoneal dialysis group before and after treatment (P＞0.05). The HR of the patients in the peritoneal dialysis group after treatment was lower than that before treatment, and the MAP was higher than that before treatment, and the differences were statistically significant (P＜0.05). The CI and MAP in the hemodialysis group after treatment were higher than those before treatment and in the peritoneal dialysis group, the HR was lower than that before treatment and in the peritoneal dialysis group, and the differences were statistically significant (P＜0.05). Conclusion The clinical treatment effect of hemodialysis therapy is significantly better than that of peritoneal dialysis. The patients with hemodialysis therapy have obvious improvement in renal function, hemodynamics are more stable, with more clinical application advantages.
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