Effect of Nimotuzumab combined with Cisplatin and Fluorouracil in the treatment of advanced nasopharyngeal carcinoma
WU Zhi-ying1 SHU Yu-xian2▲
1.Departnent of Oncological Radinotherapy,Nanchang 334 Hospital,Jiangxi Province,Nanchang 330024,China;
2.Departnent of Radinotherapy,Jiangxi Cancer Hospital,Jiangxi Province,Nanchang 330029,China
Abstract：Objective To investigate the effect of Nimotuzumab combined with Cisplatin and Fluorouracil in the treatment of advanced nasopharyngeal carcinoma.Methods A total of 50 patients with advanced nasopharyngeal carcinoma treated in Jiangxi Cancer Hospital from January 2014 to January 2012 were selected as subjects and divided into control group and the observation group by random lottery method,25 cases in each group.The control group received chemotherapy with Cisplatin and Fluorouracil.The observation group was treated with Cisplatin and Fluorouracil combined with Nitozumab chemotherapy.After 2 years follow-up,the clinical efficacy of the two groups was compared.Results The 2-year survival rate of the patients in the observation group was 88.0%,which was significantly higher than that in the control group(60.0%),and the difference was significant(P＜0.05).The QOL improvement rate of patients in the observation group was higher than that in the control group,and the difference was significant(P＜0.05).Conclusion Combined with Cisplatin and Fluorouracil in patients with advanced nasopharyngeal carcinoma,the survival time of patients can be prolonged and the quality of their life can be improved.It is worthy of clinical popularization.
吴志瑛; 舒禹先. 尼妥珠单抗联合顺铂及氟尿嘧啶治疗晚期鼻咽癌的效果[J]. 中国当代医药, 2018, 25(10): 137-139.
WU Zhi-ying;SHU Yu-xian. Effect of Nimotuzumab combined with Cisplatin and Fluorouracil in the treatment of advanced nasopharyngeal carcinoma. 中国当代医药, 2018, 25(10): 137-139.
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