Abstract：Objective To explore the change and affecting factors of blood lipid and glucose level in patients with subclinical thyroid dysfunction.Methods 300 subclinical thyroid dysfunctional patients with TSH＜0.350 mU/L received by our hospital were set as subclinical hyperthyroidism group，75 cases with TSH＞5.500 mU/L were set as subclinical hypothyroidism group，and 300 healthy examined persons were set as healthy control group from July 2011 to June 2015，then t test was used to compare the LDL，HDL，TG，TC，and GLU level between subclinical hyperthyroidism group，subclinical hypothyroidism group and healthy control group，while Pearson analysis method was used to detect the relationship between these indictors with TSH，T4，T3，FT4，and FT3，and Logistics regression was used to analyze the affecting factors for blood lipid and glucose level.Results Compared with healthy control group，HDL level in subclinical hyperthyroidism group was significantly rised (t=2.119，P=0.034)，and TC level in subclinical hypothyroidism group was significantly rised (t=2.036，P=0.042).In subclinical hyperthyroidism group，FT3level was positively correlated with HDL level (r= 0.107，P=0.009)，while in subclinical hypothyroidism group，T4level was negatively correlated with GLU level (r=-0.104，P=0.044)，FT3level was positively correlated with HDL level (r=0.105，P=0.042)，but negatively correlated with GLU level (r=-0.113，P=0.028).Smoking history was the risk factor for abnormal TG level in patients with subclinical thyroid dysfunction (P=0.023，OR=1.547，95%CI:0.740-1.806).Conclusion Blood lipid level is abnormal in patients with subclinical thyroid dysfunction，and it is related to partly indictors of thyroid function，and smoking is a risk factor in patients with dyslipidemia.
陈思梅. 亚临床甲状腺功能异常患者血脂、血糖水平的变化及相关影响因素分析[J]. 中国当代医药, 2016, 23(3): 111-114.
CHEN Si-mei. The change and affecting factors of blood lipid and glucose level in patients with subclinical thyroid dysfunction. 中国当代医药, 2016, 23(3): 111-114.
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