Abstract：Objective To explore the correlation of lesion degree of coronary angiography and cardiovascular risk factor in elderly patients with coronary heart disease.Methods 4799 elderly patients underwent coronary angiography in our hospital from January 2013 to June 2015 were selected as the research group，3589 cases of them were diagnosed as coronary heart disease，accounted for 74.79%in the total number，included 2188 male patients and 1401 female patients. The correlation of lesion degree of coronary angiography and cardiovascular risk factors in elderly patients was analyzed with one-way analysis of variance and multivariate Logistic regression analysis.Results Single risk factor analysis showed that the age，sex，hypertension，type 2 diabetes，smoking，high TC，high LDL-C and low HDL-C were correlated with the count of coronary artery disease（P＜0.05）.Logistic regression analysis showed that the age，sex，hypertension，type 2 diabetes，high TC and smoking were independent risk factors for coronary heart disease （P＜0.05），among them，type 2 diabetes was the most significant independent risk factor（P＜0.05）.After grouped by gender，Logistic regression analysis showed that type 2 diabetes remained a significant independent risk factor for coronary heart disease in men （P＜0.05），type 2 diabetes，hypertension，and smoking were independent risk factors for coronary heart disease in women （P＜0.05）. Conclusion Type 2 diabetes is a risk factor for cardiovascular disease in elderly patients with coronary heart disease，more prominent in the female group，smoking，hypertension，high TC and age should not be ignored.
戴正东;万伟;郑鹏. 老年冠心病患者心血管疾病危险因素与冠状动脉造影病变程度的相关性研究[J]. 中国当代医药, 2016, 23(10): 30-32转35.
DAI Zheng-dong;WAN Wei;ZHENG Peng. Correlation research of lesion degree of coronary angiography and cardiovascular risk factor in elderly patients with coronary heart disease. 中国当代医药, 2016, 23(10): 30-32转35.
Chen Y，Chen C，Ke X，et al.Analysis of circulating cholesterol levels as a mediator of an association between ABO blood group and coronary heart disease［J］.Circ Cardiovasc Genet，2014，7（1）：43-48.
［1］
Gu L，Liu W，Yan Y，et al.Influence of the beta-fibrinogen-455G/A polymorphism on development of ischemic stroke and coronary heart disease［J］.Thromb Res，2014，133（6）：993-1005.
［3］
Liu Y，Liu Y，Chen J，et al.The correlation of anemia and contrast-induced nephropathy in patients with chronic kidney disease undergoing percutaneous coronary intervention［J］. Zhonghua Nei Ke Za Zhi，2014，53（3）：168-173.
［6］
Ong PJ，Zeymer U，Waliszewski M，et al.Differences in clinical and angiographic profiles between Asian and Western patients with coronary artery disease：insights from the prospective"real world"paclitaxel-coated balloon registry ［J］.Int J Cardiol，2014，175（1）：199-200.
［7］
Wang W，Yang L，Tan L，et al.Arg972 insulin receptor substrate-1 polymorphism and risk and severity of Alzheimer′s disease［J］.J Clin Neurosci，2014，21（7）：1233-1237.
［8］
Zhang JM，Zhong L，Su B，et al.Perspective on CFD studies of coronary artery disease lesions and hemodynamics：a review［J］.Int J Numer Method Biomed Eng，2014，30（6）：659-680.
［9］
Packer M，Carson P，Elkayam U，et al.Effect of amlodipine on the survival of patients with severe chronic heart failure due to a nonischemic cardiomyopathy：results of the PRAISE-2 study（prospective randomized amlodipine survival evaluation［J］.JACC Heart Fail，2013，1（4）：308-314.
京公网安备 11010502046607号