Research progress of miR-212 on the regulation of diseases gene expression
LONG Fu-li1,2 PENG Zi-ming2 FENG Feng2 LIN Yong2 ZHANG Jian-ling2 QIN Yan-xin2 MAO De-wen1 WEI Ai-ling1,3▲
1.Department of Hepatology,the First Affiliated Hospital of Guangxi University of Chinese Medicine,Guangxi Zhuang Autonomous Region,Nanning 530023,China;
2.School of Graduate,Guangxi University of Chinese Medicine,Guangxi Zhuang Autonomous Region,Nanning 530200,China;
3.College of Adult Education,Guangxi University of Chinese Medicine,Guangxi Zhuang Autonomous Region,Nanning 530001,China
Abstract：miRNA is a kind of RNA molecules existing in plants and animals.Each of them can regulate one or several genes,possessing a very complex regulation network.According to the research so far,miRNA regulates one-third of human genes at least.miR-212 is a newly discovered miRNA,its expression plays a very important role in the occurrence and development of human diseases.It has great potential research value in explaining the pathogenesis of related diseases,screening diagnostic markers,treating diseases,developing new drugs and predicting disease prognosis.This paper reviews the effect of miR-212 in cancer,cardiovascular disease,neurodegenerative disease and other diseases for clinical reference.
龙富立；彭子明；冯逢；林镛；张建玲；覃艳新；毛德文；韦艾凌. miR-212对疾病基因表达调控的研究进展[J]. 中国当代医药, 2021, 28(2): 26-29.
LONG Fu-li； PENG Zi-ming； FENG Feng； LIN Yong； ZHANG Jian-ling； QIN Yan-xin； MAO De-wen；WEI Ai-ling. Research progress of miR-212 on the regulation of diseases gene expression. 中国当代医药, 2021, 28(2): 26-29.
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