Application of ultrasound conductance local drug permeation in postoperative rehabilitation of elbow joint"Terror Trilogy"
RONG Qin1 LIANG Jiao1 FANG Bing1 DENG Xian-chao1 HE Gen-lin2 CHEN Lu1 HUANG Qian1
1.The Second Department of Orthopedics,Pingxiang No.2People′sHospital in JiangxiProvince,Pingxiang 337000,China;
2.Department of Orthopedics,Luxi People′s Hospital of Pingxiang City in Jiangxi Province,Luxi 337000,China
Abstract:Objective To investigate application effect of ultrasound conductance local drug permeation in postoperative rehabilitation of elbow joint"Terror Trilogy".Methods A total of 30 patients with elbow joint"Terror Trilogy"treated in Pingxiang No.2 People′s Hospital from August 2016 to January 2018 were selected as research objects.They were divided into experimental group(15 cases)and control group(15 cases)by random number table method.The control group received conventional therapy,and the experimental group was treated with ultrasound conductance local drug permeation.The visual analogue scale(VAS)score,swelling degree of elbow joint and joint activity were compared between two groups.Results The VAS score and swelling degree of elbow joint in the experimental group were lower than those in the control group on the 5th,7th and 10th days after operation,and the differences were statistically significant(P<0.05).The joint activity of the experimental group was greater than that of the control group on the 5th,7th and 10th days after operation,and the differences were statistically significant(P<0.05).Conclusion Ultrasound conductance can relieve pain,eliminate swelling and joint activity in patients with elbow joint"Terror Trilogy"after operation.
Kannel WB,Cupples A.Epidemiology and risk profile of cardiac failure[J].Cardiovasc Drugs Ther,1988,2(1):387-395.
[16]
Dinenno FA.Skeletal muscle vasodilation during systemic hypoxia in humans[J].JAppl Physiol,2016,120(2):216-225.
[6]
Keyhani K,Héctor RG,Parsons A,et al.Intracellular drug delivery using low-frequency ultrasound:quantification of molecular uptake and cell viability[J].Pharm Res,2001,18(11):1514-1520.
[8]
Beaudin AE,Brugniaux JV,Matthias V,et al.Cerebral and myocardial blood flow responses to hypercapnia and hypoxia in humans[J].Am JPhysiol HeartCirc Physiol,2011,301(4):H1678-H1686.
[10]
Casey DP,Madery BD,Curry TB,et al.Nitric oxide contributes to the augmented vasodilatation during hypoxic exercise[J].JPhysiol,2010,588(2):373-385.
[11]
Casey DP,Madery BD,Pike TL,et al.Adenosine receptor antagonist and augmented vasodilation during hypoxic exercise[J].JAppl Physiol,2009,107(4):1128-1137.
[12]
Casey DP,Shepherd JR,Joyner MJ.Sex and vasodilator responses tohypoxiaatrest and duringexercise[J].JApplPhysiol,2014,116(7):927-936.
[13]
Casey DP,Walker BG,Curry TB,et al.Ageing reduces the compensatory vasodilatation during hypoxic exercise:the role of nitric oxide[J].JPhysiol,2011,589(6):1477-1488.
[14]
Crecelius AR,Kirby BS,Richards JC,et al.Mechanisms of ATP-mediated vasodilation in humans:modest role for nitric oxide and vasodilating prostaglandins[J].Am JPhysiol Heart Circ Physiol,2011,301(4):1302-1310.
[15]
CreceliusAR,Kirby BS,VoylesWF,etal.Augmented skeletal muscle hyperaemia during hypoxic exercise in humans is blunted by combined inhibition of nitric oxide and vasodilating prostaglandins[J].JPhysiol,2011,589(14):3671-3683.
[17]
Ellsworth ML,Ellis CG,Goldman D,etal.Erythrocytes:Oxygen sensors and modulators of vascular tone[J].Physiology,2009,24(2):107-116.
[18]
Houssiere A,Najem B,Pathak A,et al.Chemoreflex and metaboreflex responses to static hypoxic exercise in aging humans[J].Med Sci Sports Exerc,2006,38(2):305-312.
[19]
Kirby BS,Crecelius AR,VoylesWF,et al.Impaired skeletalmuscle blood flow control with advancing age in humans:attenuated ATP release and local vasodilation during erythrocyte deoxygenation[J].Circ Res,2012,111(2):220-230.
[20]
Marshall,Janice M.Interactions between local dilator and sympathetic vasoconstrictor influences in skeletal muscle in acuteand chronic hypoxia[J].Exp Physiol,2015,100(12):1400-1411.