Abstract:Objective To explore the clinical value of uterine arterial chemoembolization in the treatment of cervical carcinoma.Methods Thirty patients with cervical cancer of stageⅡa-Ⅱb treated in our hospital from March 2014 to August 2016 were selected as the study group,who underwent radical hysterectomy followed by uterine arterial chemoembolization.Thirty patients who underwent radical resection of cervical cancer at the same period were selected as the control group.The short-term efficacy,tumor shrinkage,the volume of intraoperative blood loss,operation time and postoperative pathological results were analyzed.Results After interventional treatment,the clinical symptoms of patients were relieved in different degrees,the remission rate was 100%,and the total effective rate of short-term curative effect for interventional therapy was 76.67%.There was no significant difference in the effective rate of intervention between study group at stageⅡa andⅡb (P>0.05).The tumor diameter in the study group after interventional treatment was lower than before intervention,and the difference was statistically significant (P<0.05).The volume of intraoperative blood loss in the study group was less than that in the control group,and the rate of cancer metastasis of lymph node,vascular tumor thrombus and para uterine infiltration after operation were all lower than those in the control group,and the difference was statistically significant(P<0.05).ConclusionInterventional therapy before radical resection of cervical cancer can effectively reduce the size of tumor,the short-term curative effect is obvious,and can improve the clinical symptoms of patients,effectively inhibit the cancer metastasis of lymph node,vascular tumor thrombus,and para uterine invasion,and reduce the risk of operation.
Bae JH,Lee SJ,Lee A,et al.Neoadjuvant cisplatin and etoposide followed by radical hysterectomy for stage 1B-2B cervical cancer[J].Gynecol Oncol,2008,111(3):444-844.