Effect of 3% hypertonic saline combined with Compound Ipratropium Bromide Solution atomization inhalation in the treatment of respiratory syncytial virus pneumonia
ZHANG Zhao-wen HU Bing WANG Gui-lian ZENG Kai-Dan HU Hua-zhu
Department of Pediatrics, People′s Hospital of Yichun City, Jiangxi Province, Yichun 336000, China
Abstract：Objective To investigate the effect of 3% hypertonic saline combined with Compound Ipratropium Bromide Solution atomization inhalation in the treatment of respiratory syncytial virus pneumonia. Methods A total of 195 children with respiratory syncytial virus pneumonia who were treated in People′s Hospital of Yichun City, Jiangxi Province from January 2015 to December 2016 were selected as the research subjects. According to the random number table method,they were divided into treatment group 1(65 cases),treatment group 2 (65 cases) and treatment group 3 (65 cases). The treatment group 1 received 3% hypertonic saline 4 mL + Compound Ipratropium Bromide Solution atomized inhalation. The treatment group 2 was treated with 4 mL of normal saline + Compound Ipratropium Bromide Solution atomized inhalation. The treatment group 3 was treated with 0.9% sodium chloride solution 2 mL + Terbutaline Sulfate Atomized Solution + Budesonide Suspension atomized inhalation. The time of cough disappearance, shortness of breath disappearance, asthma disappearance, lung signs disappearance, hospital stay and treatment effect of the three groups were compared. Results The disappearance time of cough, shortness of breath, dyspnea, lung signs and hospitalization time in treatment group 1 were shorter than those in treatment group 2 and treatment group 3, with statistical significances (P＜0.05). However, there were no significant differences in the disappearance time of cough, shortness of breath,dyspnea, lung signs and hospitalization time between the treatment group 2 and treatment group 3 (P＞0.05). The total effective rate of treatment group 1 was higher than that of treatment group 2 and treatment group 3, and the difference was statistically significant (P＜0.05). However, there was no significant difference in the total effective rate between the treatment group 2 and treatment group 3 (P＞0.05). Conclusion 3% hypertonic saline combined with Compound Ipratropium Bromide Solution atomization inhalation in the treatment of respiratory syncytial virus pneumonia has a high cure rate, which can relieve cough, shortness of breath, shortness of breath, lung signs and shorten the duration of hospitalization as soon as possible. It′s worth popularizing.
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