Abstract:Objective To investigate the application effect of the closed double-heated ventilator pipeline in humidification mode in mechanical ventilation patients.Methods Eighty patients applied with mechanical ventilation treated in our hospital from July 2017 to December 2018 were selected as the subjects, and divided into experimental group and control group by a random number table method, with 40 cases in each group.In the experimental group, a closed double-heated ventilator pipeline in humidification mode was used, while in the control group, normal-type non-heated ventilator pipeline in humidification mode was adopted.During the treatment, the incidence of ventilator-associated pneumonia and indicators related to pipeline nursing were observed between the two groups.Results The incidence of ventilator-associated pneumonia in the experimental group were significantly lower than those in the control group on days 14, 21 and 28 (P<0.05).There was no significant difference in ventilation time between the two groups (P>0.05).The frequency of pipeline replacement and amount of condensate water dumping in the experimental group were both less than those in the control group, the pipeline usage was longer than that in the control group, and the daily ventilator pipeline nursing time was shorter than that in the control group, and the differences were statistically significant (P<0.05).Conclusion Clinically, the closed double-heated ventilator pipeline in humidification mode significantly reduces the incidence of ventilator-associated pneumonia meeting patients′need, and ensures the quality of humidification in line with clinical requirements compared with normal-type non-heated ventilator pipeline in humidification mode.