Abstract：ObjectiveTo explore the effect of Nalbuphine in pediatric daytime operation pain in nursing.Methods136 cases of the children with unilateral hernia sac high ligation under general anesthesia in daytime operating room of Guangzhou Women and Children′s Medical Center from March to December in 2016 were selected and randomly divided into the Sufentanil group(69 cases)and the Nalbuphine group(67 cases).Patients of the Sufentanil group were given 3 ug/kg of Sufentanil,while patients of the Nalbuphine group were given 0.3 mg/kg of Nalbuphine for the induction of general anesthesia,and the patients were given placement of laryngeal mask.After operation,patients were transported to the PACU with laryngeal mask.After removal of laryngeal mask,the patients were observed for 3 h accompanied by parents.FLACC pediatric pain scale and Ramsay sedation scale were adopted to record the children′s sedation and analgesia conditions immediately after the removal of laryngeal mask(T0),1 h after removal of laryngeal mask(T1),2 h after removal of laryngeal mask (T2)and 3 h after removal of laryngeal mask (T3).The occurrence of adverse reactions during the recovery period was recorded.ResultsThe children pain scores of the Nalbuphine group at T0were higher than that of the Sufentanil group,with significant difference (P＜0.05).While the sedation scores of the Nalbuphine group at T0,T1and T2were lower than that of the Sufentanil group,with significant difference (P＜0.05).Compared with the Sufentanil group,the incidence of hypoxemia,nausea and vomiting during the recovery period was obviously decreased in the Nalbuphine group,with significant difference(P＜0.05),while there was no statistically significant difference in the incidence of other adverse effects(P＞0.05).ConclusionNalbuphine can produce longer analgesic duration than Sufentanil,and can effectively reduce the incidence of agitation and postoperative adverse reaction during the recovery period,which is appropriate for postoperative pain management of children daytime operation.
Mitchell M.Home recovery following day surgery：a patient perspective[J].J Clin Nurs，2015，24（3-4）：415-427.
[3]
左云霞，吴新民，连庆泉，等.小儿术后镇痛专家共识[Z].2014.
[5]
刘进，于布为.麻醉学.[M].北京：人民卫生出版社，2014：98-105.
[7]
Radvansky BM，Shah K，Parikh A，et al.Role of ketamine in acute postoperative pain management：a narrative review[J].Biomed Res Int，2015，2015：749837.
[10]
Argoff CE.Recent management advances in acute postoperative pain[J].Pain Pract，2014，14（5）：477-487.
[13]
Schultz-Machata AM，Becke K，Weiss M.Nalbuphine in pediatric anesthesia[J].Anaesthesist，2014，63（2）：135-143.
[2]
Wu J，Ginsberg JS，Zhan M，et al.Chronic pain and analgesic use in CKD：implications for patient safety[J].Clin J Am Soc Nephrol，2015，10（3）：435-442.
[3]
Schnabel A，Reichl SU，Zahn PK，et al.Nalbuphine for postoperative pain treatment in children[J].Cochrane Database Syst Rev，2014，31（7）：CD009583.
[4]
Yu WP，Chen Y，Duan GM，et al.Patients′perceptions of day surgery：a survey study in China surgery[J].Hong Kong Med J，2014，20（2）：134-138.
[6]
Gachon B，Nadeau C，Fritel X.Can we enhance the one-day part in breast conservative surgery[J].Bull Cancer，2015，102（12）：1002-1009.
[8]
Zeng Z，Lu J，Shu C，et al.A comparision of nalbuphine with morphine for analgesic effects and safety：meta-analysis of randomized controlled trials[J].Sci Rep，2015，3（5）：10927.
[9]
Siemianowski LA，Rosenheck JP，Whitman CB.Nalbuphineinduced psychosis treated with naloxone[J].Am J Health Syst Pharm，2014，71（9）：717-721.
[11]
Hobson A，Wiffen PJ，Conlon JA.As required versus fixed schedule analgesic administration for postoperative pain in children[J].Cochrane Database Syst Rev，2015，26（2）：CD0 11404.
[12]
Patel SK，Hanly PJ，Smith EE，et al.Nocturnal hypoxemia is associated with white matter hyperintensities in patients witha minor stroke or transient ischemic attack[J].J Clin Sleep Med，2015，11（12）：1417-1424.
[14]
Wolfe LL，Lance WR，Smith DK，et al.Novel combinations of nalbuphine and medetomidine for wildlife immobilization[J].J Wildl Dis，2014，50（4）：951-956.
[15]
Kubica-Cielińska A，Zielińska M.The use of nalbuphine in paediatric anaesthesia[J].Anaesthesiol Intensive Ther，2015，47（3）：252-256.
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