Application effect comparison the first hepatic portal blood flow occlusion method and hemi-hepatic blood flow occlusion method in the treatment of primary hepatocellular carcinoma patients with hemi-hepatectomy
ZENG San-ping
Department of Hepatobiliary Surgery, People′s Hospital in Xinyu City, Jiangxi Province, Xinyu 338000, China
Abstract:Objective To analyze the application effect of the first hepatic portal blood flow occlusion method and hemi-hepatic blood flow occlusion method in the treatment of primary hepatocellular carcinoma (HCC) patients with hemi-hepatectomy.Methods A total of 80 cases of HCC patients with hemi-hepatectomy who were treated in our hospital from October 2010 to October 2018 were selected as subjects.They were divided into study group and control group by random number table method, 40 cases in each group.The control group was treated with the first hepatic portal blood flow occlusion method, the study group was treated with the hemi-hepatic blood flow occlusion method.The recent complications, blood flow interruption time, intraoperative blood loss, postoperative hospital stay and improvement of liver function in the two groups were compared.Results There was no significant difference between the two groups in postoperative blood flow interruption time and postoperative hospital stay (P>0.05).The intraoperative blood loss in the study group was less than that in the control group, and the difference was statistically significant (P<0.05).There were no significant difference in the levels of serum alanine aminotransferase (ALT), total bilirubin (TBil) and aspartate aminotransferase (AST) before surgery between the two groups (P>0.05).After surgery, the levels of ALT, AST and TBil in both groups were lower than before surgery, and the levels of ALT, AST and TBil in the study group were lower than those in the control group, with statistically significant differences (P<0.05).The total incidence of postoperative complications in the study group was lower than that in the control group, and the difference was statistically significant(P<0.05).Conclusion For HCC patients with hemi-hepatectomy, the half-hepatic blood flow occlusion method is superior to the first hepatic portal blood flow occlusion method in protecting liver function, and it can greatly reduce the incidence of complications after operation, the curative effect is safer and more reliable.