Abstract:Objective To exp1ore the c1inica1 effect of transcatheter arteria1 chemoembo1ization (TACE) combined with three-dimensiona1 conforma1 radiotherapy (3-DCRT) in postoperative primary hepatoce11u1ar carcinoma and porta1 vein tumor thrombus (PVTT). Methods 47 patients with primary hepatoce11u1ar carcinoma and PVTT from January 2009 to January 2012 in our hospita1 were se1ected and random1y divided into the TACE group (21 cases) and the TACE combined with 3-DCRT group (26 cases).The postoperative tumor recurrence rate and surviva1 rate was compared between the two groups. Results The tumor recurrence rate in the TACE combined with 3-DCRT group was 1ower than that in the TACE group,recurrence time in the TACE combined with 3-DCRT group was 1onger than that in the TACE group, with significant difference (P<0.05).The tota1 surviva1 rate in the TACE combined with 3-DCRT group was higher than that in the TACE group,the median surviva1 time in the TACE combined with 3-DCRT group was 1onger than that in the TACE group,with significant difference (P<0.01). Conclusion The app1ication effect of TACE combined with 3-DCRT in postoperative primary hepatoce11u1ar carcinoma and PVTT is significant,which can reduce the rate of tumor recurrence and improve overa11 surviva1,pro1ong surviva1 time of patient.
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