Abstract:Objective To explore the feasibility of Pituitrin combined with Carprostol Tromethamine in the treatment of massive hemorrhage after placental abruption.Methods A total of 60 patients with placental abruption who were admitted to our hospital from June 2015 to December 2017 were selected as the research objects.All patients were divided into the treatment group(n=30)and the control group(n=30)according to random number table method.The two groups of patients underwent cesarean section,and were treated with Carprostol Tromethamine after surgery.The experimental group added Pituitrin on this basis.The prognosis,bleeding volume in different time periods,hemostasis time,total amount of bleeding,adverse reactions after treatment,Apgar score and incidence of neonatal asphyxia were compared between the two groups.Results The rate of blood transfusion and hysterectomy in the treatment group was significantly lower than that in the control group(P<0.05).The bleeding volume and total amount of bleeding at t1,t2,t3and t4in the treatment group were significantly lower than those in the control group,while the hemostasis time in the treatment group was significantly shorter than that in the control group (P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups after treatment(P>0.05).There was no significant difference in neonatal Apgar score and the incidence of neonatal asphyxia between the two groups after delivery(P>0.05).Conclusion Pituitrin-assisted Carprostol Tromethamine has a good inhibitory effect on postoperative bleeding in patients with placental abruption,and can shorten the bleeding time and reduce the total amount of bleeding,and has no significant effect on fetal delivery,and the security is also relatively good.
陈琳. 垂体后叶素联合卡前列素氨丁三醇治疗胎盘早剥产后大出血的可行性分析[J]. 中国当代医药, 2019, 26(8): 125-127转140.
C HEN Lin. Feasibility analysis of Pituitrin combined with Carprostol Tromethamine in the treatment of massive hemorrhage after placental abruption. 中国当代医药, 2019, 26(8): 125-127转140.