Abstract：Objective To explore the clinical effect of pulsed high volume hemofiltration in the treatment of acute respiratory distress syndrome.Methods A total of 52 patients with acute respiratory distress syndrome admitted to the ICU of our Hospital from February 2016 to March 2018 were enrolled.The patients were divided into the experimental group and the control group according to the random number table methods，with 26 cases in each group.The control group received conventional treatment plus conventional dose hemofiltration.The experimental group received routine treatment plus pulsed high-volume hemofiltration.The dynamic changes of vital signs and blood gas indexes before and after treatment were compared between the two groups.Results After 8 h and 24 h of treatment，the arterial pressure in the two groups was higher than that before treatment，and body temperature，respiratory rate and pulse rate after 8 h and 24 h of treatment were lower than those before treatment，the difference was statistically significant （P＜0.05）.The arterial pressure in the experimental group after 8 h and 24 h of treatment was higher than those in the control group，and body temperature，respiratory rate and pulse rate in the experimental group after 8 h and 24 h of treatment were lower than those in the control group，the difference was statistically significant （P＜0.05）.After 8 h and 24 h of treatment，the pH value and oxygen index in the two groups were higher than those before treatment，with significant difference （P＜0.05）.The oxygen index in the experimental group after 8 h of treatment was higher than that in the control group，with significant difference （P＜0.05）.Conclusion In the treatment of acute respiratory distress，pulsed high-volume hemofiltration can help improve the patients′vital signs and regulate their blood gas index，it is worthy of clinical popularization and application.
邓秀凡;邱翰忠;盘健;陈兆芸;马君武;欧相林;谢章科;朱赞东. 脉冲式高容量血液滤过治疗急性呼吸窘迫综合征的临床效果[J]. 中国当代医药, 2019, 26(4): 39-41.
DENG Xiu-fan QIU Han-zhong PAN Jian CHEN Zhao-yun MA Jun-wu OU Xiang-lin XIE Zhang-ke ZHU Zhan-dong. Clinical effect of pulsed high volume hemofiltration in the treatment of acute respiratory distress syndrome. 中国当代医药, 2019, 26(4): 39-41.
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