Abstract：Objective To investigate the clinical effect of Glargine Insulin combined with oral drug in the treatment of type 2 diabetes.Methods A total of 126 patients with type 2 diabetes treated in our hospital were selected as subjects from January 2017 to December 2017.The patients were randomly divided into single group and combined group,63 patients in each group.Patients in the single group were treated by oral administration,patients in the combined group were treated with Glargine Insulin combined with oral drug.The blood glucose(FPG,2 h PG,HbA1c)before and after treatment,the total effective rate of treatment and the incidence of hypoglycemia were compared and analyzed between the patients of two groups.Results Before treatment,there was no significant difference in blood glucose between the two groups (P＞0.05),after treatment,the blood glucose of the combined group was lower than that of the single group(P＞0.05).After treatment,the total effective rate of the combined group was 92.06%,the total effective rate of the single group was 66.67%,the total effective rate of the combined group was higher than that of the control group,the difference was statistically significant(P＜0.05).The incidence of hypoglycemia in the combined group was 3.17%,and the incidence of hypoglycemia in the single group was 14.29%,the incidence of hypoglycemia in the combined group was lower than that of the control group,and the difference was statistically significant(P＞0.05).Conclusion The clinical effect of insulin glargine combined with oral medicine in the treatment of type 2 diabetes is ideal.It is effective to control the blood sugar within the normal range and reduce the incidence of hypoglycemia.It is worth popularizing and using in clinical practice.
何凯. 甘精胰岛素联合口服药物治疗2型糖尿病的效果观察[J]. 中国当代医药, 2018, 25(29): 127-130.
HE Kai. Effect observation of applying Glargine Insulin combined with oral drug in the treatment of type 2 diabetes. 中国当代医药, 2018, 25(29): 127-130.
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