Abstract：Hemifacial Spasm，also called facial tic is one side facial muscular paroxysm non-spontaneous and non-pain recurrent rigidity or tic caused by abnormal excitement of the same side facial nerves.The pathogenesisof the disease is still unclear with slow symptoms progression and progressive development.With the widespread application of microvascular decompression，the pathogenesis of hemifacial spasm is more profoundly understood.In this article，a review is made about clinical diagnose and progress of medical and surgical treatment to improve the standardized clinical treatment of facial spasm.
Boghen DR，Lesser RL.Blepharospasm and hemifacial spasm[J].Curr Treat Options Neurol，2000，2（5）：393-400.
[1]
Auger RG，Whisnant JP.Hemifacial spasm in Rochester and Olmsted County，Minnesota，1960 to 1984[J].Arch Neurol，1990，47（11）：1233-1234.
[5]
Huh R，Han IB，Moon JY，et al.Microvascular decompression for hemifacial spasm：analyses of operative complications in 1582 consecutive patients[J].Surg Neurol，2008，69 （2）：153-157.
[12]
Patel J，Naritoku DK.Gabapentin for the treatment of hemifacial spasm[J].Clin Neuropharmacol，1996，19（2）：185-188.
[13]
Linazasoro Cristobal G.Efficacy and tolerance of gabapentin in dystonia and hemifacial spasm：a pilot study [J].Rev Neurol，2001，33（5）：408-410.
[14]
Daniele O，Caravaglios G，Marchini C，et al.Gabapentin in the treatment of hemifacial spasm[J].Acta Neurol Scand，2001，104（2）：110-112.
[15]
Dolly JO，Aoki KR.The structure and mode of action of different botulinum toxins[J].Eur J Neurol，2006，13（Suppl 4）：1-9.
[16]
Barbosa ER，Takada LT，Concalves LR，et al.Botulinum toxin type A in the treatment of hemifacial spasm：an 11-year experience[J].Arq Neuropsiquiatr，2010，68（4）：502-505.
[17]
Costa J，Espírito-Santo C，Borges A，et al.Botulinum toxin type A therapy for hemifacial spasm[J].Cochrane Database Syst Rev，2005，25（1）：CD004899.
京公网安备 11010502046607号