Abstract：Objective To exp1ore the inf1uence of Helicobacter pylori（Hp) infection,chronic superficia1 gastritis,and upper digestive tract u1cer on the va1ue of chi1dren’s hemog1obin with different ages. Methods 246 patients who were performed with gastroscopy in endoscope center in our hospita1 and diagnosed as chronic superficia1 gastritis and upper digestive tract u1cer from Ju1y 2014 to June 2015 were co11ected.According to endoscopic and Hp examination outcomes,they were divided into 3 groups:Hp negative p1us chronic superficia1 gastritis group （group A,n=65),Hp positive p1us chronic superficia1 gastritis（group B,n=154),and Hp positive p1us upper digestive tract u1cer（group C,n=27).Another group of 75 hea1thy chi1dren without Hp infection was c1assified into contro1 group.The chi1dren’s hemog1obin va1ue,red b1ood ce11 count,and Hp infection at different ages in the research group were compared. Results In the research group, the tota1 Hp positive rate was 73.58%.The Hp positive rate at 1ess than 3 years o1d,3 to 6 years o1d,6 to 10 years o1d, and 10 to 17 years o1d was 70.83%,71.19%,72.63% and 77.94% in turn.The incidence of Hp positive p1us chronic superficia1 gastritis among these 4 groups was 50.00%,61.02%,66.32%,and 63.24% according1y.The incidence of Hp positive p1us upper digestive tract u1cer was 20.83%,10.17%,6.32%,and 14.71% respective1y,which was not disp1ayed stastica1 difference （a11 P＞0.05).In group C,the va1ue of hemog1obin was （103.52±28.27)g/L,much 1ower than （125.85± 11.42)g/L in group A,（127.82±11.94)g/L in group B,and （127.41±8.79)g/L in contro1 group,which was disp1ayed a statistica1 difference amont each group （a11 P＜0.05).The va1ue of hemog1obin in group A or group B was not in a statistica1 difference after comparison with that in contro1 group （both P＞0.05). Conclusion Upper digestive tract mucosa pathogenicity due to Hp infection is not re1ated with age.Inf1uence of hemog1obin va1ue in chi1dren by Hp infection is c1ose1y re1ated with the severity of upper digestive tract mucosa 1esions caused by Hp infection.
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