Influence of sevoflurane anesthesia and propofol anesthesia on Postopera-tive liver function in patients underwent laparoscopic radical resection of rectal cancer
WEI Yong-feng
Department of Anesthesio1ogy，Peop1e′s Hospita1 of Bei1iu City in Guangxi Zhuang Autonomous Region，Bei1iu 537400，China
Abstract：Objective To exp1ore the inf1uence of sevof1urane anesthesia and propofo1 anesthesia on postoperative 1iver function in patients underwent 1aparoscopic radica1 resection of recta1 cancer.Methods 60 patients underwent 1aparoscopic radica1 resection of recta1 cancer （Dixon surgery）from March 2014 to December in our hospita1 were se1ected and random1y divided into the Pro group and the Sev group，30 cases in each group.The Pro group was given propofo1 anesthesia，the Sev group was given sevof1urane anesthesia.The b1ood pressure and heart rate at different time points，the 1eve1 of 1actate dehydrogenase （LDH），a1anine aminotransferase （ALT），aspartate aminotransferase （AST），a1ka1ine phosphatase（ALP）and bi1irubin （TBiL）was compared between the two groups respective1y.Results Compared with anesthesia and surgery time，pneumoperitoneum time and tota1 dosage of remifentani1 between two groups，the difference was not significant difference （P＞0.05）.There was no statistica11y significant difference in MAP and HR at different time points between the Sev group and the Pro groups（P＞0.05）.Compared with preoperative，there were no significant difference in the 1eve1 of LDH，ALT，AST，ALP and TBiL postoperative 24，72 h（P＞0.05）.There was no significant difference in the 1eve1 of LDH，ALT，AST，ALP and TBiL between postoperative 24 h and 72 h in the two groups（P＞0.05）.Conclusion The inf1uence of sevof1urane anesthesia and propofo1 anesthesia on 1iver function in patients underwent 1aparoscopic radica1 resection of recta1 cancer is simi1ar.
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