Abstract:Objective To observe benefits of postprandia1 b1ood g1ucose se1f-monitoring to b1ood g1ucose,b1ood 1ipid,body mass index(BMI)and cardiovascu1ar events(CVE)of type 2 diabetic patients with qua1ified b1ood sugar contro1. Methods 124 patients treated in our hospita1 from Ju1y 2012 to September 2014 were se1ected and random1y divided into study group (n=60)and contro1 group (n=64).Sing1e-centre,open,random,para11e1ed contro1 study was adopted,inc1uding screening period(≤4 d)and open treatment period(24 weeks).Patients in the study group were given at 1east a set(7 times)of b1ood g1ucose profi1e monitoring per week and were permitted to adjust diet by se1f,whi1e patients in the contro1 group were not given forcefu11y postprandia1 b1ood g1ucose monitoring and were permitted to perform fasting b1ood g1ucose monitoring and to adjust diet by se1f.The b1ood g1ucose of these patients were monitored regu1ar1y and fo11owed up by te1ephone,and the primary end point was change of g1ycosy1ated hemog1obin (HbA1c)1eve1 at 24 weeks compared with base1ine va1ue.Results After 24 weeks of treatment,the 1eve1 of HbA1c,BMI,and trig1yceride(TG)in the study group were significant1y 1ower than those at base1ine(P<0.05),but there was no significant difference in 1ow density 1ipoprotein(LDL)(P>0.05).In the contro1 group,there were no significant differences in HbA1c,BMI,TG and LDL between 24 weeks of treatment and at base1ine (P>0.05).Conclusion Positive postprandia1 b1ood g1ucose monitoring can bring further benefits to b1ood g1ucose,b1ood 1ipid,and BMI in type 2 diabetic patients with qua1ified b1ood g1ucose contro1.
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