Abstract:Objective To understand the distribution of clinical isolates pathogenic bacteria in Jinzhou Central Hospital (“our hospital”for short)in 2015,and provide reference for rational selection of antibiotics in clinic.Methods All kinds of clinical specimens of hospitalized patients were collected from January to December 2015 in our hospital.1568 strains of pathogenic bacteria were detected.The identification and drug sensitivity of clinical isolates were identified by VITEK-2,and the data were statistically analyzed by WHONET 5.6 software.Results In 1568 strains of pathogenic bacteria,including 1163 strains of Gram negative bacteria accounted for 74.2%,312 strains of Gram positive bacteria accounted for 19.9%,93 strains of funguses accounted for 5.9%.The separation rate of the top four Gram negative bacteria were Klebsiella pneumoniae,Escherichia coli,Pseudomonas aeruginosa and Acinetobacter Baumannii;the top three Gram positive bacteria were Staphylococcus aureus,Enterococcus faecalis and Staphylococcus epidermidis.Gram positive bacteria for Linezolid,Vancomycin,Tigecycline,Quinupristin/Dalfopristin,Furantoin were almost completely sensitive.Gram negative bacteria were commonly used in the clinical treatment of a variety of antimicrobial drugs.Conclusion Gram negative bacteria were the main pathogens of nosocomial infection in the hospital.The detection rate of resistant bacteria is high.The monitoring of drug resistant bacteria should be strengthened,and the rational selection of antibiotics to prevent and control the production and spread of drug resistant strains effectively.
刘郁. 2015年锦州市中心医院住院患者感染病原菌分布及耐药性分析[J]. 中国当代医药, 2016, 23(31): 135-138.
LIU Yu. Analysis of distribution and drug resistance of pathogenic bacteria in hospitalized patients of Jinzhou Central Hospital in 2015. 中国当代医药, 2016, 23(31): 135-138.