ObjectiveTo probe into the effects of guided education and nursing in promoting rehabilitation of children with cerebral palsy.Methods80 cases of children with cerebral palsy and who included from December 2014 to April 2017 were grouped into the research，and the children were randomly divided into experimental group and control group，40 cases in each group.The control group was received routine rehabilitation nursing intervention，while the experimental group was received guided education and nursing.Then，the rehabilitation of the two groups of children after intervention for 5 months were statistically compared.ResultsAfter the nursing intervention for 5 moths，the effective rate of nursing in the experimental group was 82.50% （33/40），which was higher than that in the control group of 62.50%(25/40）.Before the nursing，the life ability and intelligence score of two groups were lower，and the difference was not statistically significant（P＞0.05）.After the nursing intervention for 5 moths，the scores of two groups were improved.There were statistical differences before and after comparison （P＜0.05）;The experimental group was better than that the control group （P＜0.05）;The family satisfaction in the experimental group was 92.50%（37/40），which was higher than that in the control group of 80.00%（32/40）.ConclusionThe implementation of guided education and nursing care for children with cerebral palsy which can greatly improve the intelligence and life ability of children，and this method can be used in clinical practice.