Abstract：ObjectiveTo study the effect of GuizhiFuling Pills combined with Mifepristone in the treatment of hysteromyoma and its influence on hormone levels and hemorheology.MethodsFrom August 2015 to August 2016,100 patients with uterine fibroids treated in our hospital were selected and evenly divided into experimental group and control group according to the simple randomization.In the experimental group,patients were treated with Mifepristone combined with GuizhiFuling Pills.In the control group,only Mifepristone was used.The therapeutic effect after 3-month courses of treatment was compared.Besides,the average size of uterine fibroids,the change of hormone levels,and the change of hemorheology in the two groups before and after treatment were compared.ResultsAfter therapy,the total effective rate was 92.0%in the experimental group,much higher than that in the control group(78.0%),the difference was statistically significant(P＜0.05);the size of uterine fibroids after therapy in the experimental group was smaller than that in the control group (P＜0.05).The indexes of blood viscosity,plasmaviscosity,hematocrit and platelet aggregation rate were significantly lower after therapy compared with those before treatment,and those indexes in the experimental group were greatly lower than the control group,the differences were statistically significant(P＜0.05).ConclusionCombination of GuizhiFuling Pills and Mifepristone can obtain an optimal effect on treating uterine fibroids.It reduces the size of hysteromyoma,decreases the levels of LH,FSH,P,and E2,as well as the hemodynamic indexes including blood viscosity,plasmaviscosity,hematocrit and platelet aggregation rate,which is worthy of clinical promotion.
谢晓虹. 桂枝茯苓丸联合米非司酮治疗子宫肌瘤的效果及对激素水平和血液流变学的影响[J]. 中国当代医药, 2017, 24(20): 103-105.
XIE Xiao-hong. Effect of GuizhiFuling Pills combined with Mifepristone on hysteromyoma and its influence on hormone level and hemorheology. 中国当代医药, 2017, 24(20): 103-105.
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