超选介入化疗联合放疗对脑胶质细胞瘤术后抑制残留细胞的疗效研究

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摘要目的分析超选介入化疗联合放疗对脑胶质细胞瘤术后抑制残留细胞的疗效。方法选取2014年1月～2016年1月于我院行肿瘤切除术的脑胶质细胞瘤患者52例，根据患者自愿入组原则，分为观察组（n=28）与对照组（n=24）。观察组患者给予超选介入化疗联合放疗治疗，对照组患者给予系统放疗联合化疗，比较两组患者的治疗效果。结果观察组患者的治疗效果显著优于对照组（P＜0.05）；两组患者的不良反应发生率差异无统计学意义（P＞0.05）；观察组患者的预后效果显著优于对照组（P＜0.05）；观察组患者 Karnofsky评分[（71.78±4.83）分]显著高于对照组[（59.93±5.17）分]，两组比较差异有统计学意义（P＜0.05）。结论超选介入化疗联合放疗能够有效抑制消除脑胶质细胞瘤术后残留细胞，预后效果较好。

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	涂勤

关键词 ：脑胶质细胞瘤, 超选介入化疗, 放疗

Abstract：ObjectiveTo analyze the efficacy of super-selective interventional chemotherapy combined with radiotherapy in inhibition of residual cell after brain glioma surgery.M ethodsAltogether 52 patientswith cerebral gliomawho underwent tumor resection from January 2014 to January 2016 treated in our hospitalwere selected and divided into observation group(n=28)and control group(n=24)according to the principle of voluntary admission.Patients of observation group were treated with super-selective interventional chemotherapy combined with radiotherapy,while patients of control group were treated with systematic radiotherapy combined with chemotherapy.The therapeutic effect between the two groups was compared.ResultsThe curative effect of observation group was significantly better than that of control group(P＜0.05).The incidence of adverse reactions between the two groups had no statistically significant difference(P＞0.05).The prognosis of patients of observation group was significantly better than that of control group (P＜0.05).The Karnofsky score of observation group[(71.78±4.83)points]was significantly higher than that of control group[(59.93±5.17)points],with statistically significant difference between the two groups(P＜0.05).ConclusionSuper-selective interventional chemotherapy combined with radiotherapy can effectively inhibit and eliminate residual cells after brain glioma resection,and the prognosis effect is better.

Key words： Brain glioma Super-selective interventional chemotherapy Radiotherapy

作者简介: 涂勤（1985-），男，湖北孝感人，本科，研究方向：胶质瘤

引用本文:

涂勤. 超选介入化疗联合放疗对脑胶质细胞瘤术后抑制残留细胞的疗效研究[J]. 中国当代医药, 2017, 24(22): 39-41.
TU Qin. Effect study of super-selective interventional chemotherapy combined w ith radiotherapy in inhibition of residual cell after brain glioma surgery. 中国当代医药, 2017, 24(22): 39-41.

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