Abstract:Objective To investigate the high-risk factors of abdominal distension in patients with type Ⅱrespiratory failure using non-invasive mechanical ventilation. Methods The clinical data of 118 patients with type Ⅱrespiratory failure who underwent non-invasive mechanical ventilation in Beijing Fengtai Hospital from January 2019 to November 2020 were retrospectively analyzed, and the high-risk factors of abdominal distension in patients with type Ⅱrespiratory failure after non-invasive mechanical ventilation were analyzed. Results After non-invasive mechanical ventilation treatment, 52 cases (44.07%) of type Ⅱrespiratory failure patients with abdominal distension, 66 cases(55.93%) without abdominal distension; univariate analysis showed that age, self-feeding, gastrointestinal decompression,open-mouth breathing, 24 h total ventilation time, electrolyte changes and gastrointestinal function changes were associated with abdominal distension after non-invasive mechanical ventilation in patients with type Ⅱrespiratory failure, and the difference was statistically significant (P<0.05). Gender, nasal feeding, exhalation positive pressure support, inhalation positive pressure support, lung infection had no significant difference with abdominal distension after non-invasive mechanical ventilation (P>0.05). Multivariate analysis showed that age ≥60 years (β=1.059, OR=2.884, 95%CI=1.322-6.292), open-mouth respiration (β=2.216, OR=9.173, 95%CI= 3.939-21.364), 24 h total ventilation time ≥10 h (β=1.866, OR=6.462, 95%CI= 2.767-15.090), electrolyte changes (β=2.659, OR=14.280, 95%CI= 5.815-35.065), gastrointestinal function changes (β=1.427, OR=4.167, 95%CI=1.819-9.546) were associated with abdominal distension after non-invasive mechanical ventilation in patients with type Ⅱrespiratory failure (P<0.05).Conclusion Abdominal distension in patients with type Ⅱrespiratory failure after non-invasive mechanical ventilation is closely related to age, mouth-opening breathing, total time of 24 h ventilation, changes in electrolytes, and changes in gastrointestinal function, and clinical attention should be paid to it.